Results 81 to 90 of about 66,141 (268)
A Bayesian framework to estimate diversification rates and their variation through time and space [PDF]
Background: Patterns of species diversity are the result of speciation and extinction processes, and molecular phylogenetic data can provide valuable information to derive their variability through time and across clades.
Schnitzler, Jan +8 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Supplementary Material for the manuscript "Robustness of Divergence Time Estimation Despite Gene Tree Error: A Case Study of Fireflies (Coleoptera: Lampyridae)"
Catalán, Ana +3 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Estimation for conditional moment models based on martingale difference divergence
We provide a new estimation method for conditional moment models via the martingale difference divergence (MDD). Our MDD-based estimation method is formed in the framework of a continuum of unconditional moment restrictions.
Song, Kunyang, Jiang, Feiyu, Zhu, Ke
core +2 more sources
Phylogenetic placement of the mysterious Malagasy genus Ambrella H. Perrier (Vandeae, Orchidaceae)
IntroductionThe monotypic genus Ambrella H. Perrier, endemic to Madagascar and traditionally placed within the subtribe Angraecinae, has long poses a challenge in terms of its phylogenetic classification.MethodsTo clarify the evolutionary position of ...
Sławomir Nowak +4 more
doaj +1 more source
Divergence Time Estimation of Aloes and Allies (Xanthorrhoeaceae) Based on Three Marker Genes
Aloes and allies are prominent members of African succulent vegetation and especially of the highly diverse Cape Flora. The main goal of this study was to obtain age estimates for alooids by calibrating a Bayesian phylogenetic analysis based on two ...
Zeinab Khodaei +2 more
doaj +1 more source
Estimating Divergence Times in the Presence of an Overdispersed Molecular Clock [PDF]
Molecular loci that fail relative-rate tests are said to be "overdispersed." Traditional molecular-clock approaches to estimating divergence times do not take this into account. In this study, a method was developed to estimate divergence times using loci that may be overdispersed.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

