Results 61 to 70 of about 140,611 (264)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Impact of Exchange Characteristics on Customer Profitability: A Case Study of a Ceramic Tile Manufacturing Company

open access: yesRomanian Economic Journal
This study was conducted in a ceramic tile production company to test the impact of a set of exchange characteristics on customer profitability. After developing hypotheses based on previous studies, we prepared the company's sales database, which ...
Salah Eddine Kout
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development of a qPCR and a Lamp Assay for Verticillium longisporum Detection and a Triplex qPCR Assay for Simultaneous Detection of V. longisporum, Leptosphaeria biglobosa, and L. maculans from Canola Samples

open access: yesPhytoFrontiers
Verticillium wilt, Verticillium stem striping, and Verticillium stripe are common disease names that all denote infection caused by Verticillium longisporum on canola or other brassica crops.
Heting Fu   +13 more
doaj   +1 more source

Soil microbial functionality in response to the inclusion of cover crop mixtures in agricultural systems

open access: yesSpanish Journal of Agricultural Research, 2016
Agricultural systems where monoculture prevails are characterized by fertility losses and reduced contribution to ecosystem services. Including cover crops (CC) as part of an agricultural system is a promising choice in sustainable intensification of ...
Diego N. Chavarría   +7 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The transmission and influence mechanism of bitcoin, green bonds, renewable energy, and gold: a quantile connectedness approach

open access: yesFrontiers in Blockchain
The study examined the connectedness among bitcoin, green bonds (represented by the US S&P Green Bond Index), renewable energy (represented by the OMX Biofuel Index), and gold, utilizing a novel quantile connectedness approach from 14 November 2017 ...
Amro S. Alamaren   +4 more
doaj   +1 more source

Impact of the Russian-Ukrainian armed conflict on the financial performance of Armenia’s banking sector [PDF]

open access: yesBanks and Bank Systems
The importance of this study is underscored by the increasing significance of economic resilience in the face of global instability. The Russian-Ukrainian armed conflict, initiated by Russia in 2022, has caused profound shifts in the geopolitical and ...
Armen Hakobyan, Zaven Margaryan
doaj   +1 more source

Home - About - Disclaimer - Privacy