Results 121 to 130 of about 6,654,400 (432)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
International Journal for Equity in HealthBackground The level of experienced sociocultural pressure to have an idealized body can vary depending on a person’s gender identity and sexual orientation.
Nikola Komlenac +3 more
doaj +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2014 Plant genetic resources (PGR) have been used in breeding programs for many decades to produce modern varieties by introducing genes of interest, in particular, resistance genes.
A. Didier +7 more
doaj
Formalising lexical and syntactic diversity for data sampling in French [PDF]
arXivDiversity is an important property of datasets and sampling data for diversity is useful in dataset creation. Finding the optimally diverse sample is expensive, we therefore present a heuristic significantly increasing diversity relative to random sampling. We also explore whether different kinds of diversity -- lexical and syntactic -- correlate, with
arxiv
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Improving Structural Diversity of Blackbox LLMs via Chain-of-Specification Prompting [PDF]
arXivThe capability to generate diverse text is a key challenge facing large language models (LLMs). Thus far, diversity has been studied via metrics such as $n$-gram diversity or diversity of BERT embeddings. However, for these kinds of diversity, the user has little control over the dimensions along which diversity is considered.
arxiv
FACTORS DETERMINING CONJUGATION IN PARAMECIUM AURELIA II. GENETIC DIVERSITIES BETWEEN STOCKS OR RACES [PDF]
, 1936 T. M. Sonneborn, B M Cohen
openalex +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source