Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Unitary Space Time Constellation Analysis: An Upper Bound for the Diversity [PDF]
The diversity product and the diversity sum are two very important parameters for a good-performing unitary space time constellation. A basic question is what the maximal diversity product (or sum) is.
Han, Guangyue, Rosenthal, Joachim
core +1 more source
Sedimentary DNA Reveals Cyanobacterial Community Diversity over 200 Years in Two Perialpine Lakes [PDF]
Marie‐Ève Monchamp +3 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review [PDF]
H Meier +5 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Diversity Report 2000-2001 [PDF]
This document is an analysis of the Diversity Plan for the 2000-2001 academic year. Each of the objectives is defined in detail, citing examples of success from specific departments.
The Ohio State University. Council on Diversity
core
Type II Supernova Spectral Diversity. II. Spectroscopic and Photometric Correlations [PDF]
Claudia P. Gutiérrez +9 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cross-Chemistry Leads to Product Diversity from Atromentin Synthetases in Aspergilli from Section Nigri [PDF]
Elena Geib +4 more
openalex +1 more source

