Supporting Educational Excellence in Diversity (SEED): faculty development and allyship
BMC Medical EducationIntroduction Bias, privilege, microaggressions, and other forms of mistreatment negatively impact students’ learning, professional development, wellness, and identity.
Puja Chadha +6 more
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DEVELOPMENT AND UNDERDEVELOPMENT: The Latin American Tradition: Essays on the Unity and the Diversity of Latin American Culture. C
, 1968 Karl H. Schwerin
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
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On the Diversity of Infective Matter, and the Division of Syphilitic Forms of Disease Founded Thereon [PDF]
Curt D. Sigmund
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ON THE RELATION BETWEEN THE PRODUCTIVITY, BIOMASS, DIVERSITY, AND STABILITY OF A COMMUNITY [PDF]
, 1965 Egbert Giles Leigh
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Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
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Chromosomes and causation of human cancer and leukemia: I. Karyotypic diversity in a single cancer [PDF]
, 1966 Avery A. Sandberg, Kiyomi Yamada
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
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