Results 161 to 170 of about 7,598,050 (355)
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
J. Caporaso +7 more
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Effect of boundary vegetation and landscape features on diversity and abundance of breeding bird communities of abandoned crop fields in southwest Poland [PDF]
Grzegorz Orłowski
openalex +1 more source
Determination of Genetic Diversity in Some Pumpkin Genotypes Using SSR Marker Technique
Ömer Faruk Çoşkun
openalex +2 more sources
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Racial Diversity Deficit in College Football: Fixing the Pipeline
Keali‘i Troy Kukahiko
openalex +2 more sources
L-diversity: privacy beyond k-anonymity
Ashwin Machanavajjhala +3 more
semanticscholar +1 more source

