Results 171 to 180 of about 6,654,400 (432)

UA12/6 Black History Month Calendar of Events [PDF]

open access: yes, 1999
Schedule of Black History Month events produced by Minority Student Support ...
WKU Diversity Programs
core   +2 more sources

Can LLMs Generate Diverse Molecules? Towards Alignment with Structural Diversity [PDF]

open access: yesarXiv
Recent advancements in large language models (LLMs) have demonstrated impressive performance in molecular generation, which offers potential to accelerate drug discovery. However, the current LLMs overlook a critical requirement for drug discovery: proposing a diverse set of molecules.
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

UA12/6 Black Awareness Week Memorial Service [PDF]

open access: yes, 1972
Program from the Black Awareness Week memorial service held April 16, 1972 to honor Martin Luther King, Malcomb X, Medger Evers, Emmet Till, Dwight Smith, Kay Smith, Robert Kinslow and Eddie ...
WKU Diversity Programs
core   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

UA12/6 Black Awareness Week Schedule of Events [PDF]

open access: yes, 1971
Schedule of Black Awareness Week ...
WKU Diversity Programs
core   +1 more source

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