A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Optimizing board structure for ESG integrity: Nonlinear size effects and diversity moderation on greenwashing. [PDF]
Yu J, Hwang YS.
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Plant diversity influences plant volatile emission with varying effects at the species and community levels. [PDF]
Medina-van Berkum P +15 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
LGBTIQA+ Inclusion in Aged Care: Perspectives From Providers and Community Stakeholders. [PDF]
Tissot D +3 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Nutrient Addition Has a Stronger Effect Than Intraspecific Genetic Diversity on Critical Ecological Responses in a Salt Marsh Foundation Species. [PDF]
Tomasula J +5 more
europepmc +1 more source
New analysis for consistency among markers in the study of genetic diversity: development and application to the description of bacterial diversity [PDF]
Sandrine Pavoine, Xavier Bailly
openalex +1 more source

