Results 211 to 220 of about 7,002,212 (409)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

CLONAL DIVERSITY IN THE UNISEXUAL FISH POECILIOPSIS MONACHA‐LUCIDA : A TISSUE GRAFT ANALYSIS [PDF]

, 1979
Robert A. Angus, Jack C. Schultz
openalex   +1 more source

iNEXT: an R package for rarefaction and extrapolation of species diversity (Hill numbers)

, 2016
T. Hsieh, K. Ma, A. Chao
semanticscholar   +1 more source

The effect of <i>Beta vulgaris</i> on an <i>in vitro</i> oral microbiome of electronic cigarette users. [PDF]

J Oral Microbiol
Staton DV, Tang J, Barbisan M, Nussbaum J, Baker JL.   +4 more
europepmc   +1 more source

Minutes, Diversity Council Meeting, Tuesday, March 31, 2020 [PDF]

, 2020
Diversity Council,
core   +1 more source

Minutes, Diversity Council Meeting, Tuesday, March 1, 2022 [PDF]

, 2022
Diversity Council,
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Lost in translation: advancing intervention adaptation for populations with non-dominant language preference in high diversity settings. [PDF]

Implement Sci Commun
Austad K, Cordova-Ramos EG, Fernandez A, Drainoni ML.   +3 more
europepmc   +1 more source

Minutes, Diversity Council Meeting, Tuesday, November 24, 2020 [PDF]

, 2020
Diversity Council,
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source