Results 211 to 220 of about 7,274,781 (400)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Genetic diversity and relationships of broomcorn millet based on trnT-trnL and GBSSI sequences. [PDF]
Yu X+11 more
europepmc +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Assessing the Vegetation Diversity of Different Forest Ecosystems in Southern Romania Using Biodiversity Indices and Similarity Coefficients. [PDF]
Stamin FD, Cosmulescu S.
europepmc +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Community phylogenetic diversity drives flowering synchrony among coexisting plant species even under drought conditions. [PDF]
Luzuriaga AL+3 more
europepmc +1 more source
iNEXT: an R package for rarefaction and extrapolation of species diversity (Hill numbers)
T. Hsieh, K. Ma, A. Chao
semanticscholar +1 more source