Results 221 to 230 of about 7,274,781 (400)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

A common grounded ultra-wideband diversity/MIMO antenna with high inter-element isolation. [PDF]

Sci Rep
Shailesh, Srivastava G, Kumar S, Sharma D, Goyal B, Soliman NF.   +5 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Standardized diversity estimation uncovers global distribution patterns and drivers of stream insects. [PDF]

NPJ Biodivers
Liu G, Lin Z, Soininen J, Dalu T, Juvigny-Khenafou NPD, Khan S, Mu H, Oduro C, Qi X, Qu X, Riis T, Wijewardene L, Zhang M, Li J, Wu Y, Wu N.   +15 more
europepmc   +1 more source

Understanding Fathering: Masculinity, Diversity and Change [PDF]

, 2009
Hauari, Hanan, Hollingworth, Katie
core   +2 more sources

Species Diversity in Space and Time.

, 1996
A. Magurran, M. Rosenzweig
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Global increase in the endemism of birds from north to south. [PDF]

Nat Commun
Dehling DM, Chown SL.
europepmc   +1 more source

t-Closeness: Privacy Beyond k-Anonymity and l-Diversity

IEEE International Conference on Data Engineering, 2007
Ninghui Li, Tiancheng Li, Suresh Venkatasubramanian   +2 more
semanticscholar   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source