Results 231 to 240 of about 6,268,242 (306)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Stool and vaginal microbiome profiles patterns among Black and White endometrial cancer survivors: A pilot study in North Carolina. [PDF]

PLoS One
Jin M, Keku T, McCoy A, Brown JA, Peterson M, Hunter J, Smith S, Black-Grant S, Yates MS, Peery AF, Bae-Jump VL, Azcarate-Peril MA, Engel SM, Olshan AF, Nichols HB.   +14 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Human landscape disturbance and wildlife gut microbiota: global knowledge gaps. [PDF]

PeerJ
Paleo-López R, Ugarte CS, Stuardo CJ, Silva AX, Napolitano C.   +4 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Synchronous and Asynchronous Variation of Taxonomic and Phylogenetic Diversity During the Succession of <i>Pinus kesiya</i> var. <i>langbianensis</i> Forest in Yunnan, China. [PDF]

Ecol Evol
Wang X, Ma Y, Zhao B, Chen D, Luo Y, Peng M, Li Y, Zhou X, Chen W, Tang CQ, Wang C.   +10 more
europepmc   +1 more source

Compressing Diversity: Ethnicization of the Workforce and Outsourcing of Social Reproduction as Assets for the Italian Fashion Industry

, 2016
Antonella Ceccagno
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Changes in Fish Taxonomic and Phylogenetic Diversity and Their Driving Factors in a Reservoir in the Karst Basin of Southwest China. [PDF]

Animals (Basel)
Qiao J, Liu Y, Yao W, Ma H, Yu L, Zhao Q, Ouyang L.   +6 more
europepmc   +1 more source