Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Plant Species Diversity Improves Soil Physicochemical Traits and Modulates Soil Microbial Community Structure, with a Pronounced Enhancement of Fungal Diversity in Urban Forests. [PDF]
Plants (Basel)Song YH +8 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Diversify and conquer: How effector diversity is shaped by host-microbe co-evolution. [PDF]
PLoS PathogMüller MC +5 more
europepmc +1 more source
Embracing Linguistic Diversity: Pre-Service Teachers’ Lesson Planning for English Language Learning in Sweden [PDF]
BethAnne Paulsrud, Parvin Gheitasi
openalex +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Variability, Drivers, and Utility of Genetic Diversity-Area Relationships in Terrestrial Vertebrates. [PDF]
Ecol LettSchmidt C +4 more
europepmc +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Species Interactions Determine the Importance of Response Diversity for Community Stability to Pulse Disturbances. [PDF]
Ecol LettKunze C +3 more
europepmc +1 more source