Results 51 to 60 of about 4,758,383 (290)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Student Walkout Protest for Diversity Center Need
, 2015 A video of the student walkout protest that occurred for the students’ demand for a diversity centerWalkout ...
Juarez, Dominick
core +1 more source
, 2018 A photo of a shirt donated by Dominick Juarez that was worn during the student walkout to show the need for a Diversity center on campusDemonstration ...
Ashmawi, Mariam, Juarez, Dominick
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Diversity Plans Can’t Breathe without AIIR: Building a High-Caliber Diversity Initiative [PDF]
, 2018 For one intensive month this summer, we participated in an online leadership development program, the National Inclusive Excellence Leadership Academy (NIXLA), with nearly 100 leaders from across the country.
Milton, Lyonel +5 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Diversity Plans: an Analysis 2008-2009 [PDF]
, 2009 This is the analysis of the 2008-2009 Diversity Action Plan, which contains an executive summary as well as audits of the participating departments and offices.
The Ohio State University. Council on Diversity
core +1 more source
Diversity Center Progress, March 2017
, 2017 A copy of an update on the diversity center progress with a timeline last updated on March 24.Documents and ...
Unknown
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source