Results 81 to 90 of about 6,654,400 (432)

How Far Can We Extract Diverse Perspectives from Large Language Models? [PDF]

open access: yesarXiv, 2023
Collecting diverse human opinions is costly and challenging. This leads to a recent trend in exploiting large language models (LLMs) for generating diverse data for potential scalable and efficient solutions. However, the extent to which LLMs can generate diverse perspectives on subjective topics is still unclear.
arxiv  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Diverse Beliefs [PDF]

open access: yesSSRN Electronic Journal, 2009
This paper presents a general framework for studying diverse beliefs in dynamic economies. Within this general framework, the characterization of a central-planner general equilbrium turns out to be very easy to derive, and leads to a range of interesting applications.
Angus A Brown, L C G Rogers
openaire   +2 more sources

Diversity & Inclusion Update - Fall 2018

open access: yes, 2018
This Fall 2018 newsletter discusses ongoing campus initiatives to facilitate diversity and inclusion efforts on campus. Topics discussed include continued campus changes inspired by the January 2016 Town Hall meeting, such as the expansion of the Office ...
Office of Diversity & Inclusion,
core   +3 more sources

The diversity and biogeography of soil bacterial communities.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2006
For centuries, biologists have studied patterns of plant and animal diversity at continental scales. Until recently, similar studies were impossible for microorganisms, arguably the most diverse and abundant group of organisms on Earth.
N. Fierer, R. B. Jackson
semanticscholar   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Diversity-By-Design for Dependable and Secure Cyber-Physical Systems: A Survey [PDF]

open access: yesarXiv, 2020
Diversity-based security approaches have been studied for several decades since the 1970's. The concept of diversity-by-design emerged in the 1980's and, since then, diversity-based system design research has been explored to build more secure and dependable systems.
arxiv  

iNEXT: an R package for rarefaction and extrapolation of species diversity (Hill numbers)

open access: yes, 2016
Hill numbers (or the effective number of species) have been increasingly used to quantify the species/taxonomic diversity of an assemblage. The sample‐size‐ and coverage‐based integrations of rarefaction (interpolation) and extrapolation (prediction) of ...
T. Hsieh, K. Ma, A. Chao
semanticscholar   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

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