Results 41 to 50 of about 2,834,442 (291)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Recent Trends in Archaeological Theory: Some Comments [PDF]
This paper is a selective review of some recent themes in archaeological theory since c.2000. It deals first with a philosophical pragmatism and its application to archaeological thought and practice.
Matthew Johnson
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
The Hoax Phenomenon in Indonesian Society: Observing Anti-Diversity Memes since 2014
This article seeks to explain whether anti-diversity hoaxes that become viral on mass media disrupt the institutional memory of kebhinekaan (diversity) in Indonesian society.
Aprinus Salam
doaj +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The Political Sources of Solidarity in Diverse Societies [PDF]
Building and sustaining solidarity is an enduring challenge in all liberal-democratic societies. Ensuring that individuals are willing to accept these “strains of commitment,” to borrow John Rawls’ apt phrase, has been a worry even in relatively homogeneous societies, and the challenge seems even greater in ethnically and religiously diverse societies.
BANTING, Keith, KYMLICKA, Will
openaire +2 more sources
The dance of psychotherapy and politics [PDF]
This paper presents a review of and commentary on the edited collection The Politics of Psychotherapy: New Perspectives. Certain chapters and themes are picked up and elaborated upon. The impact of modernist ‘audit culture’ values on therapy practice are
House, Richard
core
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source

