Results 11 to 20 of about 5,723 (132)

The human colon: Evidence for degenerative changes during aging and the physiological consequences

Neurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Uncomplicated Diverticulosis Is Not Associated With Abdominal Pain or Abnormal Bowel Habit—A Population‐Based Swedish Cohort Study

Neurogastroenterology &Motility, Volume 37, Issue 6, June 2025.
ABSTRACT Background Whether uncomplicated diverticulosis gives rise to symptoms is controversial. Diary‐based studies of abdominal pain and stool habits in general populations are scarce, and we therefore investigated symptom patterns in diverticulosis from prospectively collected symptom diaries in a random sample of the general population who ...
Bjarki T. Alexandersson, Michael P. Jones, Anna Forsberg, Charlotte R. H. Hedin, Ellionore Järbrink‐Sehgal, Susanna Walter, Nicholas J. Talley, Lars Agreus, Anna Andreasson, Peter T. Schmidt   +9 more
wiley   +1 more source

Updated evidence on epidemiology, diagnosis, and treatment for colonic diverticular bleeding

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Since 2020, multiple large‐scale studies (CODE BLUE‐J) in Japan have accelerated the accumulation of evidence on colonic diverticular bleeding (CDB). This review summarizes the latest findings regarding CDB epidemiology and endoscopic hemostasis.
Chikamasa Ichita, Takaaki Kishino, Tomonori Aoki, Tomohiko Machida, Takashi Murakami, Yoshinori Sato, Naoyoshi Nagata   +6 more
wiley   +1 more source

Case Report: Intestinal Diverticulum in a Golden Retriever

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A 1‐year‐old female spayed Golden Retriever presented with a 2‐day history of vomiting and a chronic 4‐month history of intermittent diarrhoea. Owners elected to pursue exploratory laparotomy where a firm, tan, irregular structure was observed in the right caudal abdomen with a small adhesion to an adjacent loop of jejunum. The structure was removed en
Emily Eppler, Alyssa Motz
wiley   +1 more source

Phenotypical Characterization of Gastroenterological and Metabolic Manifestations in Patients With Williams–Beuren Syndrome

American Journal of Medical Genetics Part A, Volume 197, Issue 6, June 2025.
ABSTRACT Gastrointestinal (GI) symptoms are common in patients with Williams–Beuren syndrome (WBS), but their prevalence and possible causes are not yet fully known. This study assessed GI symptoms' prevalence and their possible origin by performing a predefined set of tests in adult WBS patients.
Maria Francesca Bedeschi, Annarita Baldassarri, Roberta Villa, Federico Tanzi, Simona Salera, Vincenza Lombardo, Alessandro Draghi, Nicole Piazza O'Sed, Giovanni Casazza, Maurizio Vecchi, Mirella Fraquelli   +10 more
wiley   +1 more source

Surgical outcomes of colorectal cancer surgery in transplant recipients: A matched case–control study

Colorectal Disease, Volume 27, Issue 6, June 2025.
Abstract Aim The incidence of colorectal carcinoma (CRC) in transplant (TX) recipients is higher than in the general population. Registry data indicate inferior oncological outcomes for this population. While the general surgical risk is increased in TX recipients, the risk associated with elective CRC surgery in this population is not well ...
Phil Meister, Samira Vestweber, Jan Neuhaus, Marc A. Reschke, Ulf Neumann, Andreas D. Rink   +5 more
wiley   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, Volume 12, Issue 20, May 29, 2025.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Three timepoint perioperative CEA levels are a prognostic factor for recurrence after adjuvant chemotherapy in patients with Stage II and III colorectal cancer

Annals of Gastroenterological Surgery, Volume 9, Issue 3, Page 496-504, May 2025.
This study aimed to investigate the relationship between the three timepoint perioperative CEA (ttpCEA) calculated at three timepoints and recurrence during the perioperative period in Stage II and III colorectal cancer (CRC) patients. A total of 538 patients were included for the training data and 329 patients for validation data, and 5‐y time‐to ...
Shodai Mizuno, Kohei Shigeta, Ryosuke Hara, Kyoko Sakamoto, Jumpei Nakadai, Hideo Baba, Hiroto Kikuchi, Yoko Adachi, Takehiro Shimada, Hirofumi Suzumura, Kiyoaki Sugiura, Shimpei Matsui, Ryo Seishima, Koji Okabayashi, Yuko Kitagawa   +14 more
wiley   +1 more source

Perforation of the Sigmoid Colon due to Diverticular Rupture in a Woman With FKBP14‐Related Kyphoscoliotic Ehlers‐Danlos Syndrome: A Case Report

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT This report highlights that severe manifestations of intestinal fragility can occur in kyphoscoliotic EDS, as already described in vascular EDS.
Malika Foy, Valentin Renault, Fabrice Gillas, Philippe De Mazancourt, Robert Carlier, Gilles Manceau, Karelle Bénistan   +6 more
wiley   +1 more source

Gastrointestinal Perforations Associated With JAK Inhibitors: A Disproportionality Analysis of the FDA Adverse Event Reporting System

United European Gastroenterology Journal, Volume 13, Issue 4, Page 566-575, May 2025.
ABSTRACT Background Gastrointestinal perforations have been reported in a small number of rheumatoid arthritis (RA) patients treated with Janus kinase (JAK) inhibitors in clinical trials. However, large‐scale postmarketing data repositories are needed to further investigate this potentially rare but serious adverse event.
Adam Goldman, Emanuel Raschi, Amit Druyan, Kassem Sharif, Adi Lahat, Ilan Ben‐Zvi, Shomron Ben‐Horin   +6 more
wiley   +1 more source