Results 91 to 100 of about 105,757,333 (286)

An Asymptotic Stability Theorem for Divide-and-Conquer Sequences

open access: yes, 2021
Divide-and-conquer is a popular strategy to design algorithms. It splits the input into several smaller subproblems, solving each subproblem separately, and thencombine together to solve the original problem.The analysis of such divide-and-conquer ...
Guedj, Michael
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Synthesizing Divide-and-Conquer Programs

open access: yes, 2022
Multicore computers today are ubiquitous, from large distributed systems to desktops and mobile phones. Their complex memory architecture enables fast and efficient execution when used correctly.
Nicolet, Victor
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Efficient Square-Based Montgomery Multiplier for All Type C.1 Pentanomials

open access: yesIEEE Access, 2018
In this paper, we present a low complexity bit-parallel Montgomery multiplier for $GF(2^{m})$ generated with irreducible Type C.1 pentanomials $x^{m}+x^{m-1}+x^{k}+x+1$ . Based on a combination of generalized polynomial basis (GPB) squarer and a newly
Yin Li, Xingpo Ma, Qing Chen, Chuanda Qi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Exploiting Plaintiffs Through Settlement: Divide and Conquer [PDF]

open access: yes, 2007
This paper considers settlement negotiations between a single defendant and $N$ plaintiffs when there are fixed costs of litigation. When making simultaneous take-it-or-leave-it offers to the plaintiffs, the defendant adopts a divide and conquer strategy.
Che, Yeon-Koo   +2 more
core   +1 more source

Exploiting Plaintiffs Through Settlement: Divide and Conquer

open access: yes
This paper considers settlement negotiations between a single defendant and $N$ plaintiffs when there are fixed costs of litigation. When making simultaneous take-it-or-leave-it offers to the plaintiffs, the defendant adopts a divide and conquer strategy.
Che, Yeon-Koo, Spier, Kathryn
core   +1 more source

Putting Theory into Practice: Using a Human Rights Framework and Grassroots Organizing to Build a National Revolutionary Movement

open access: yesColumbia Journal of Race and Law, 2019
This Essay proposes to use the theoretical framework of Critical Race Theory and Marxism to chart a way forward and away from the Tea Party’s racist dream and toward revolution.
Bekah Mandell
doaj   +1 more source

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