Results 81 to 90 of about 105,757,333 (286)

Measuring phacoemulsification groove depth using probe tip dimensions and biometry lens thickness readings

open access: yesClinical Ophthalmology, 2016
Kevin Dunne, Alex J Buller Department of Ophthalmology, Hawkes Bay District Health Board, Hastings, New Zealand Aim: To describe a useful technique utilizing lens thickness from biometric data as well as phacoemulsification (phaco) probe tip ...
Dunne K, Buller AJ
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Domains Characterizations of Divide-and-Conquer Sequences

open access: yes, 2020
Divide-and-conquer is a popular strategy to design algorithms. It splits the input into several smaller subproblems, solving each subproblem separately , and then combine together to solve the original problem.
Guedj, Michael
core  

Resultados de la técnica de facoemulsificación "Divide y Vencerás" en la cirugía de catarata Results of the "Divide and Conquer"phacoemulsification technique in the cataract surgery

open access: yesRevista Cubana de Oftalmología, 2010
OBJETIVO: Valorar la técnica de facoemulsificación de "Divide y Vencerás" en la cirugía del cristalino en el Centro de Microcirugía Ocular del Instituto Cubano de Oftalmología "Ramón Pando Ferrer".
Juan Raúl Hernández Silva   +5 more
doaj  

A divide-and-conquer reconstruction method for defending against adversarial example attacks

open access: yesVisual Intelligence
In recent years, defending against adversarial examples has gained significant importance, leading to a growing body of research in this area. Among these studies, pre-processing defense approaches have emerged as a prominent research direction. However,
Xiyao Liu   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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