Results 51 to 60 of about 366 (206)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Kinematic Identification of Parallel Mechanisms by a Divide and Conquer Strategy. [PDF]

open access: yes, 2010
Institute for Systems and Technologies of Information, Control and Communication, International Federation of Automatic ...
Durango S.   +4 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Novel Network for Change Detection Based on a Divide-and-Conquer Fusion Strategy

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Change detection (CD) is a fundamental task that is pivotal in understanding surface changes. Recently, CD methods have advanced rapidly and attained impressive results, driven by deep learning technology.
Mengmeng Wang   +5 more
doaj   +1 more source

Scalability and Validation of Big Data Bioinformatics Software

open access: yesComputational and Structural Biotechnology Journal, 2017
This review examines two important aspects that are central to modern big data bioinformatics analysis – software scalability and validity. We argue that not only are the issues of scalability and validation common to all big data bioinformatics analyses,
Andrian Yang   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Production Optimization – Facilitated by Divide and Conquer Strategies

open access: yesIFAC-PapersOnLine, 2015
Abstract This paper explores the use of divide and conquer algorithms to solve production optimization problems. Exploitation of inherent structure facilitates efficient formulations and solutions to production optimization problems that frequently appear in the upstream oil and gas sector.
Bjarne Foss   +2 more
openaire   +1 more source

Divide-and-Conquer: Frequency-Domain Decoupling Strategy for Low-Light Remote Sensing Image Enhancement

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Low-light remote sensing (RS) images typically cover vast areas. They contain objects of various scales and have localized light sources. This makes it challenging to enhance brightness while preserving fine image structures.
Bosong Zhuang   +3 more
doaj   +1 more source

Robust Clustered Support Vector Machine With Applications to Modeling of Practical Processes

open access: yesIEEE Access, 2018
Real datasets are often distributed nonlinearly. Although many least squares support vector machine (LS-SVM) methods have successfully modeled this kind of data using a divide-and-conquer strategy, they are often ineffective when nonlinear data are ...
Xin-Jiang Lu   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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