Results 61 to 70 of about 366 (206)

Symbolic Abstractions with Guarantees: A Data-Driven Divide-and-Conquer Strategy

2023 62nd IEEE Conference on Decision and Control (CDC), 2023
This article is concerned with a data-driven divide-and-conquer strategy to construct symbolic abstractions for interconnected control networks with unknown mathematical models. We employ a notion of alternating bisimulation functions (ABF) to quantify the closeness between state trajectories of an interconnected network and its symbolic abstraction ...
openaire   +2 more sources

Unveiling fine-scale spatial structures and amplifying gene expression signals in ultra-large ST slices with HERGAST

Nature Communications
We propose HERGAST, a system for spatial structure identification and signal amplification in ultra-large-scale and ultra-high-resolution spatial transcriptomics data.
Yuqiao Gong, Xin Yuan, Qiong Jiao, Zhangsheng Yu   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A geometric consistency constrained hierarchical global SfM for large-scale UAV images

International Journal of Applied Earth Observations and Geoinformation
Efficient and effective pose estimation and 3D point clouds reconstruction from low-altitude UAV images is crucial for digital twins and geospatial applications.
Yan Zhou, Xianwei Zheng, Jinding Gao, Qian Shi, Xiaoping Liu   +4 more
doaj   +1 more source

Speech Acts and Sub-Sentential Speech

Crítica, 2018
In this paper, I compile some reasons for resisting Stainton’s (2006) analysis of sub-sentential speech. My resistance stems from considerations about the intentions and expectations of those who communicate using sub-sentential speech.
J. Robert Thompson
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Multiple Vessel Cooperative Localization Under Random Finite Set Framework With Unknown Birth Intensities

IEEE Access, 2020
The key challenge for multiple vessel cooperative localization is considered as data association, in which state-of-the-art approaches adopt a divide-and-conquer strategy to acquire measurement-to-target association.
Feihu Zhang, Le Li, Lichuan Zhang, Guang Pan   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source