Results 81 to 90 of about 10,260 (285)
Scalability and Validation of Big Data Bioinformatics Software
Computational and Structural Biotechnology Journal, 2017 This review examines two important aspects that are central to modern big data bioinformatics analysis – software scalability and validity. We argue that not only are the issues of scalability and validation common to all big data bioinformatics analyses,
Andrian Yang +2 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Nature CommunicationsWe propose HERGAST, a system for spatial structure identification and signal amplification in ultra-large-scale and ultra-high-resolution spatial transcriptomics data.
Yuqiao Gong +3 more
doaj +1 more source
Robust Clustered Support Vector Machine With Applications to Modeling of Practical Processes
IEEE Access, 2018 Real datasets are often distributed nonlinearly. Although many least squares support vector machine (LS-SVM) methods have successfully modeled this kind of data using a divide-and-conquer strategy, they are often ineffective when nonlinear data are ...
Xin-Jiang Lu +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A geometric consistency constrained hierarchical global SfM for large-scale UAV images
International Journal of Applied Earth Observations and GeoinformationEfficient and effective pose estimation and 3D point clouds reconstruction from low-altitude UAV images is crucial for digital twins and geospatial applications.
Yan Zhou +4 more
doaj +1 more source
International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, 2015 The exponential and rapid growth of the E-commerce based both on the new opportunities offered by the Internet, and on the spread of the use of debit or credit cards in the online purchases, has strongly increased the number of frauds, causing large ...
Roberto Saia, L. Boratto, S. Carta
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Speech Acts and Sub-Sentential Speech
Crítica, 2018 In this paper, I compile some reasons for resisting Stainton’s (2006) analysis of sub-sentential speech. My resistance stems from considerations about the intentions and expectations of those who communicate using sub-sentential speech.
J. Robert Thompson
doaj +1 more source
Kinematic identification of parallel mechanisms by a divide and conquer strategy
, 2021 This paper presents a Divide and Conquer strategy to estimate the kinematic parameters of parallel symmetrical mechanisms. The Divide and Conquer kinematic identification is designed and performed independently for each leg of the mechanism.
Achiche S. +4 more
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