Results 161 to 170 of about 13,062 (288)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Parallel Divide and Conquer on Meshes

open access: yes, 1996
We address the problem of mapping divide-and-conquer programs to mesh connected multicomputers with wormhole or store-and-forward routing. We propose the binomial tree as an efficient model of parallel divide-and-conquer and present two mappings of the ...
X. Zhong, J. Telle, V. Lo, S. Rajopadhye
core  

Divide and conquer acoustic diversity. [PDF]

open access: yesEMBO J, 2021
Gómez-Casati ME, Goutman JD.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Parallel Divide and Conquer

open access: yes, 1991
We develop a generic divide and conquer algorithm for a parallel tree machine. From the generic algorithm we derive balanced, parallel versions of quicksort and the fast Fourier transform by substitution of data types, variables and statements.
Hansen, Per Brinch
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

WITHDRAWN: Common NLRP3 inflammasome inhibitors and Covid-19: Divide and Conquer. [PDF]

open access: yesSci Afr, 2021
Batiha GE   +6 more
europepmc   +1 more source

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