Results 81 to 90 of about 13,062 (288)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An Asymptotic Stability Theorem for Divide-and-Conquer Sequences

open access: yes, 2021
Divide-and-conquer is a popular strategy to design algorithms. It splits the input into several smaller subproblems, solving each subproblem separately, and thencombine together to solve the original problem.The analysis of such divide-and-conquer ...
Guedj, Michael
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Domains Characterizations of Divide-and-Conquer Sequences

open access: yes, 2020
Divide-and-conquer is a popular strategy to design algorithms. It splits the input into several smaller subproblems, solving each subproblem separately , and then combine together to solve the original problem.
Guedj, Michael
core  

Synthesizing Divide-and-Conquer Programs

open access: yes, 2022
Multicore computers today are ubiquitous, from large distributed systems to desktops and mobile phones. Their complex memory architecture enables fast and efficient execution when used correctly.
Nicolet, Victor
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The design of divide and conquer algorithms

open access: yes, 1985
The structure common to a class of divide and conquer algorithms is represented by a program scheme. A theorem is presented which relates the functionality of a divide and conquer algorithm to its structure and the functionalities of its subalgorithms ...
Smith, Douglas R.
core   +1 more source

Resultados de la técnica de facoemulsificación "Divide y Vencerás" en la cirugía de catarata Results of the "Divide and Conquer"phacoemulsification technique in the cataract surgery

open access: yesRevista Cubana de Oftalmología, 2010
OBJETIVO: Valorar la técnica de facoemulsificación de "Divide y Vencerás" en la cirugía del cristalino en el Centro de Microcirugía Ocular del Instituto Cubano de Oftalmología "Ramón Pando Ferrer".
Juan Raúl Hernández Silva   +5 more
doaj  

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