Results 91 to 100 of about 5,190,616 (233)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

How the Effect of Virtual Reality on Cognitive Functioning Is Modulated by Gender Differences

Bioengineering
Virtual reality (VR) can be a promising tool to simulate reality in various settings but the real impact of this technology on the human mental system is still unclear as to how VR might (if at all) interfere with cognitive functioning. Using a computer,
Stefania Righi, Gioele Gavazzi, Viola Benedetti, Giulia Raineri, Maria Pia Viggiano   +4 more
doaj   +1 more source

Brain activity during divided and selective attention to auditory and visual sentence comprehension tasks

Frontiers in Human Neuroscience, 2015
Using functional magnetic resonance imaging, we measured brain activity of human participants while they performed a sentence congruence judgment task in either the visual or auditory modality separately, or in both modalities simultaneously. Significant
Mona eMoisala, Mona eMoisala, Viljami eSalmela, Viljami eSalmela, Emma eSalo, Synnöve eCarlson, Synnöve eCarlson, Virve eVuontela, Oili eSalonen, Kimmo eAlho, Kimmo eAlho, Kimmo eAlho, Kimmo eAlho   +12 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

No-onset looming motion guides spatial attention [PDF]

These 6 experiments explored the ability of moving random dot patterns to attract attention, as measured by a simple probe-detection task. Each trial began with random motion (i.e., dots linearly moved in random directions).
von Mühlenen, Adrian, Lleras, Alejandro
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Component-Specific Advantages in Visual Attention Across Experience Groups: A UFOV Study

Behavioral Sciences
Visual attention involves the efficient allocation of processing resources across space and under conditions of visual competition. This study examined whether experience-related advantages in visual attention are expressed uniformly or selectively ...
Siyu Guo, Ziyao Liu, Lu Yin, Zhao Li, Yingzhi Lu   +4 more
doaj   +1 more source

Emotional stimuli, divided attention, and memory

, 2005
The emotion-memory literature has shown that negative emotional arousal enhances memory. S. A. Christianson (1992) proposed that preattentive processing could account for this emotion-memory relationship.
Holmes, Katherine, Rosalie P. Kern, Katherine Holmes, Libkuman, Terry M., Kern, Rosalie P., Otani, Hajime, Terry M. Libkuman, Hajime Otani   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source