Results 81 to 90 of about 5,190,616 (233)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Divided executives and democratisation [PDF]
, 2006 This article examines the effect of a divided executive on democratisation in mixed systems where presidents are directly elected and prime ministers are responsible to the legislature.
McMenamin, Iain, Elgie, Robert
core +2 more sources
Eye-tracking Deaf and hearing viewing of sign language interpreted news broadcasts
Journal of Eye Movement Research, 2014 In this study, the viewing habits of deaf and hearing adults are investigated using eye tracking while they watched interpreted news broadcasts. The study shows that deaf viewers primarily focus on the interpreter and secondarily access picture material,
Jennifer Wehrmeyer
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Frontiers in Psychology, 2017 In recent years, the interest in Attention Deficit and Hyperactivity Disorder (ADHD) and its relation to deficits in working memory (WM) and more specifically the different executive functions (EFs) has grown, to the point of confirming that these are ...
M. Rosa Elosúa +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Orthostatic Cognitive Dysfunction in Postural Tachycardia Syndrome After Rapid Water Drinking
Frontiers in Neuroscience, 2019 Background: Postural tachycardia syndrome (POTS) is a form of autonomic dysregulation and is characterized by an excessive heart rate (HR) increment upon the upright body position while blood pressure is maintained.
Belén Rodriguez +5 more
doaj +1 more source
Divided attention after closed head injury
, 2003 One of the most persisting sequelae of closed head injury (CHI) is a general slowing of information processing. With neuropsychological testing, the effect is already apparent in simple reaction time tests. The slowing is more pronounced in complex tasks
Withaar, F.K, Brouwer, W.H.
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source