Murine IL-2 outperforms human IL-2 in supporting the survival of naïve mouse CD8 T cells in vitro. [PDF]
Life Sci AllianceYu Y +8 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
A biomechanical comparison of closed-reduction osteosynthesis techniques for fractures of the ulnar styloid. [PDF]
J Orthop Surg ResEck J +7 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Effects of High-Intensity Interval Training on Cardiorespiratory Fitness and Cardiometabolic Health in Real-World Settings: A Systematic Review and Meta-Analysis. [PDF]
Sports (Basel)Stefanovic J, Werndle VV, Reljic D.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Divided Spirits Tequila, Mezcal, and the Politics of Production
, 2015 Divided Spirits tells the stories of tequila and mezcal, two of Mexico's most iconic products. In doing so, the book illustrates how neoliberalism influences the production, branding, and regulation of local foods and drinks.
Bowen, Sarah
core
Changes in the proportion of suicides attributed to work-related problems before, during, and after the COVID-19 pandemic in Japan. [PDF]
Environ Occup Health PractEguchi H, Nakata A.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Schur Multipliers of Divided Differences and Multilinear Harmonic Analysis
It was first shown by D. Potapov and F. Sukochev in 2009 that Lipschitz functions are also operator-Lipschitz on Schatten class operators Sp, 1<p<∞, which is related to a conjecture by M. Krein.
Reimann, Jesse (author)
core