Social compatibility in opposite-sex prairie vole pairs is modulated by early-life sleep experience. [PDF]
Bueno-Junior LS +8 more
europepmc +1 more source
Jewish sepulchral heritage in silesian voivodeship divided by the borders. Similarities and differences [PDF]
Majewska, Anna
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Changes in cardiovascular health and physical functioning in non-hospitalized, adult COVID-19 patients after 3 years of follow-up. [PDF]
Vloet JIA +6 more
europepmc +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Longitudinal assessment of growth velocity in relation to pubertal timing, IGF-I, fasting insulin and fat mass in healthy boys. [PDF]
Sørensen K +4 more
europepmc +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Understanding impact factor and citescore. [PDF]
Borkar NK, Nair AS, Meshram S.
europepmc +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Lateralized costs of divided attention to faces. [PDF]
Lee SC, Strother L.
europepmc +1 more source

