Results 71 to 80 of about 1,805,244 (300)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Divided difference operators in equivariant KK-theory [PDF]
Journal of Topology and Analysis, 2014 Let G be a compact connected Lie group with a maximal torus T. Let A, B be G-C*-algebras. We define certain divided difference operators on Kasparov's T-equivariant KK-group KKT(A, B) and show that KKG(A, B) is a direct summand of KKT(A, B). More precisely, a T-equivariant KK-class is G-equivariant if and only if it is annihilated by an ideal of ...
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Polynomials, Divided Differences, and Codes
Proceedings of Innovations in Theoretical Computer Science Conference (ITCS)Multivariate multiplicity codes (Kopparty, Saraf, and Yekhanin, J. ACM 2014) are linear codes where the codewords are described by evaluations of multivariate polynomials (with a degree bound) and their derivatives up to a fixed order, on a suitably chosen affine point set.
openaire +4 more sources
Weighted Means of B-Splines, Positivity of Divided Differences, and Complete Homogeneous Symmetric Polynomials [PDF]
, 2020 Albrecht Boettcher +3 more
openalex +1 more source
A Sound Source Localization Method Based on Frequency Divider and Time Difference of Arrival [PDF]
, 2023 Jianchun Zhao +6 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2017 This paper is devoted to the study of a multi-step method with divided differences for solving nonlinear equations in Banach spaces. In earlier studies, hypotheses on the Fréchet derivative up to the sixth order of the operator under consideration is ...
Ioannis K. Argyros, Santhosh George
doaj +1 more source