Results 81 to 90 of about 4,917,341 (287)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A modified Newton-secant method for solving nonsmooth generalized equations

open access: yesMathematical Modelling and Analysis
In this paper, we study the solvability of nonsmooth generalized equations in Banach spaces using a modified Newton-secant method, by assuming a Hölder condition.
Vitaliano de Sousa Amaral   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Limit Sets for Natural Extensions of Schelling's Segregation Model

open access: yes, 2010
Thomas Schelling developed an influential demographic model that illustrated how, even with relatively mild assumptions on each individual's nearest neighbor preferences, an integrated city would likely unravel to a segregated city, even if all ...
Singh, Abhinav   +2 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Multi-Media As a Cognitive Tool [PDF]

open access: yes, 2002
Two of the modalities used to present information to students, namely, animation and verbal representation are in a constant competition in effectiveness, without any persistent winner, except when it comes to conceptual versus procedural knowledge ...
Alkhalifa, Dr Eshaa M.
core  

Divided difference operators in equivariant KK-theory [PDF]

open access: yesJournal of Topology and Analysis, 2014
Let G be a compact connected Lie group with a maximal torus T. Let A, B be G-C*-algebras. We define certain divided difference operators on Kasparov's T-equivariant KK-group KKT(A, B) and show that KKG(A, B) is a direct summand of KKT(A, B). More precisely, a T-equivariant KK-class is G-equivariant if and only if it is annihilated by an ideal of ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

C 1,1 functions and optimality conditions [PDF]

open access: yes
In this work we provide a characterization of C 1,1 functions on Rn (that is, differentiable with locally Lipschitz partial derivatives) by means of second directional divided differences.
La Torre Davide, Rocca Matteo
core  

ANALISA GAMBARAN POST MORTEM MAKROSKOPIS DAN MIKROSKOPIS ORGAN PARU DAN USUS HALUS PADA TIKUS WISTAR SETELAH PEMBERIAN WARFARIN LD-50 DAN LD-100 [PDF]

open access: yes, 2015
Introduction : More than 800.000 people died every years from suicide, and in 2012 suicidal acts on 15-29 years old become the second most cause. Suicide by poison is one of the most used, Warfarins role here aside from its therapeutical effect as ...
Amarwati, Siti   +2 more
core   +1 more source

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