Results 131 to 140 of about 108,961 (314)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

EVOLUTIONARY AND MOLECULAR BIOLOGY: SCIENTIFIC PERSPECTIVES ON DIVINE ACTION

open access: yes, 1998
Introduction / Robert John Russell -- Message to the Vatican Observatory Conference on Evolutionary and Molecular Biology / Pope John Paul II -- Message to the Pontifical Academy of Sciences / Pope John Paul II -- Evolution and the human person: the ...

core  

Examining the effect of entrepreneurial work environment on the innovative work behavior of employees : Management

open access: yes
The study aimed to examine the effect of an entrepreneurial work environment on the innovative work behaviour of the employees. To support the theories of the study, literature was reviewed. The study follows a research methodology and uses a descriptive
Matias, Rey Mark Paul   +4 more
core   +1 more source

The God who Gives: Philo and Paul in Conversation [PDF]

open access: yes, 2013
This thesis sets Philo of Alexandria and the apostle Paul in conversation on divine grace. While scholars have occasionally observed that Philo and Paul both speak about God’s generosity, studies and comparisons of their particular theologies of grace ...
MCFARLAND, ORREY,WAYNE
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Introduction. What Does a Divine Name Do? [PDF]

open access: yes
The paper aims at exploring the many facets and uses of divine names incontexts. It provides a typology to clarify“what does a divine name do”: spatialize,describe, appropriate, connect, and praise/exalt.
Bonnet, Corinne
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Divine Comédie : divine justice

open access: yes, 2014
Il peut sembler banal de s’intéresser à la «divine justice» dans la Divine Comédie. A. Pézard. R. Dragonetti et les critiques italiens ont, en effet, mis en lumière, et de façon magistrale, les différents aspects de ce qui constitue le thème majeur de l ...
Dauphine, James
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The effect of pressure on the viscosity of the molten alkali nitrates

open access: yes, 1981
The variation of the shear viscosities of the molten alkali nitrates has been measured as a function of pressure to 1.5 x 108 Pascal for fixed temperatures to 715K.
Divine, Paul Christopher John
core  

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