Results 71 to 80 of about 293,961 (344)

St. Ignatius as psychotherapist? How Jesuit spirituality and wisdom can enhance psychotherapy [PDF]

open access: yes, 2020
The great wisdom traditions associated with various religious and spiritual practices and institutions have offered a variety of helpful strategies for more effective living and coping with life’s many challenges.
Plante, Thomas G
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

DIVINE POWER AND THE SPIRITUAL LIFE IN AQUINAS [PDF]

open access: yesStudia Gilsoniana, 2017
The role of divine power in Aquinas’s spiritual doctrine has often been neglected in favor of a focus on the primacy of charity, the controlling virtue of spiritual progress. The tendency among some thinkers (e.g.
Heather M. Erb
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Substance and Person in Tertullian and Augustine [PDF]

open access: yes, 2018
The doctrine of the Trinity has been a focal point of Christian thinking throughout Church history. While the term “Trinity” does not appear in the biblical text, it is still a vital Christian doctrine.
Hillaker, Andrew P
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

NILAI KETUHANAN SEBAGAI LANDASAN PERBAIKAN KEHIDUPAN BERBANGSA DAN BERNEGARA

open access: yesJurnal Ilmu Agama: Mengkaji Doktrin, Pemikiran, dan Fenomena Agama, 2017
One of the most fundamental identities of a religion is the divine doctrine or doctrine that recognizes the existence of God. It can even be said is not a religion if there is no main characteristic that is the recognition and confidence of God.
Muhammaddin Muhammaddin
doaj   +1 more source

Eros in the first century’s Christian theology [PDF]

open access: yes, 2015
For among most contemporaries, the concept of Eros seems to have nothing to do with Christianity. Sifting through the psychoanalysis of sexual fantasy, theologically it says nothing.
Marica, Adrian Mircea
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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