Results 71 to 80 of about 201,281 (315)

Mulla Sadra on the Problem of Evil [PDF]

open access: yesحکمت صدرایی, 2015
In this article, Mulla Sadra’s account of the problem of evil is considered. He is one of the philosophers who attempt to provide logical solutions for the problems which stem from divine attributes (omniscience, omnipotence and goodness) by appeal to ...
معصومه عامری   +1 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Divine voluntarism: moral obligation supervenes on God's antecedent will [PDF]

open access: yes, 2004
Divine voluntarism (Divine command theory) is a series of theories that claim that God is prior to moral obligation and that moral obligation is determined by God's will.
Nam, Mi Young
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

In search of a timeless God

open access: yes, 2013
In contemporary discussions it is often assumed that God cannot be timeless if presentism is true, but that God can be timeless if four-dimensional eternalism is true.
Mullins, Ryan
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Divine Simplicity and Naming God

open access: yes, 2023
This essay explores the doctrine of divine simplicity (DDS) within the framework of classical theism, addressing its compatibility with the plurality of divine attributes.
Martin, Michael
core  

AL-GHAZĀLĪ\u27S DIVINE COMMAND THEORY: Biting the Bullet

open access: yes, 2021
This article reviews al-Ghazālī\u27s conception of Divine Command Theory (DCT) in light of contemporary philosophical developments. There are two well-known objections against DCT.
Shoaib Ahmed Malik, Malik, Shoaib Ahmed
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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