Results 31 to 40 of about 8,921 (255)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Importance of Prayer for Šīʿa Muslims [PDF]

open access: yesEdinost in Dialog
Human being is a combination of body and divine soul, and as body needs daily nutrition, soul needs it too – in a form of prayer and supplication. Spirituality and connection to the source of this soul which is God, the Almighty is the main goal of ...
Taher Amini Golestani
doaj   +1 more source

The Light of the World: Mediating Divine Presence through Light and Sound in a Contemporary Megachurch [PDF]

open access: yesMaterial Religion, 2020
The paper explores the interplay of elaborate light and sound technologies used in the worship services of Lakewood Church in Houston, Texas. During the renovation and reconstruction of the church venue from former basketball stadium to church auditorium, the church hired professional companies to design and outfit the huge 16,000 seat auditorium in ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

“The Human Was Created Out of Haste.” On Prophecy and the Problem of Human Nature in the Qur’an

open access: yesReligions, 2021
In this article it is argued that the Qur’an’s doctrine of divine mercy is best understood in light of its pessimistic anthropology, an aspect of the text that is often underappreciated.
Gabriel Said Reynolds
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Les contacts ethniques dans la Mésopotamie et les syncrétismes de la religion sumérienne

open access: yesScripta Instituti Donneriani Aboensis, 1969
In this paper, the author explores ethnic relations in Mesopotamia and syncretism in Sumerian religion in the light of political and religious conflicts, and divine democracy.
J. Van Dijk
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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