Results 51 to 60 of about 8,890 (257)

FALSIFIABILITY AND TRACTION IN THEORIES OF DIVINE ACTION

open access: yesZygon, 2010
One of the most focused research programs in the science‐religion dialogue that has taken place up to the present is the series of volumes published jointly by the Vatican Observatory and the Center for Theology and the Natural Sciences.
doaj   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Trinitizing the Universe: Teilhard’s Theogenesis and the Dynamism of Love

open access: yesOpen Theology, 2018
The God-world relationship bears an ambiguous relationship between God’s immanent life and God’s life in history. The development of the doctrine of the Trinity in the early Church gave rise to a distinction between theologia and oikonomia. Bonaventure’s
Delio Ilia
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Bonaventure: education for beauty in the knowledge of the world and of God - doi: 10.4025/actascieduc.v36i1.22268

open access: yesActa Scientiarum. Education, 2014
In the Middle Ages, the increasing autonomy on the nature of Beauty may be defined by three aspects that underscore the speculative approach on the concept: first, the Neoplatonic root in strict relationship with the Good (kalon); second, the Augustinian
Gerald Cresta
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Love as the Warp and Weft of Creation: The Theological Aesthetics of Muhammad Iqbal and Rabindranath Tagore

open access: yesOpen Theology
In this article, I explore in a comparative key the theological aesthetics of the celebrated poets Muhammad Iqbal (1877–1938) and Rabindranath Tagore (1861–1941).
Khalid Hina
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Illuminating Causality: The Role of Light in Thomas Aquinas’s Metaphysics of Being

open access: yesReligions
In this article, we hold a strong thesis, i.e., that light is the conceptual resource that best explains the creative act in Thomas Aquinas’s metaphysics.
Jorge Eduardo Arbeláez   +1 more
doaj   +1 more source

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