Results 71 to 80 of about 8,921 (255)

THE REFLECTION OF PANTHEISM’S PRINCIPLES OF IBN ARAB IN AHMED KHANI'S WORKS"

open access: yesگۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆ
The concept of pantheism is among the most profound and influential intellectual theories in Islamic mysticism, particularly within Sufism. The idea of pantheism, which reached its pinnacle in the works of the Andalusian Mystic Ibn Arab (1164–1240 CE ...
Waheed Ramadhan, Shvan Hassan
doaj   +1 more source

“The Road of Payback” and Rabbinic Judaism

open access: yesReligions, 2019
In Anger and Forgiveness, Martha Nussbaum argues against the claim that the suffering of the wrongdoer restores, or partially restores, what was damaged by the wrongdoing. Making this mental mistake sets a person on “the road of payback,” and
Jonathan Schofer
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Poem Lifting Us Up to the Divine Guardian

open access: yesKeria: Studia Latina et Graeca
The article focuses on the role of Pindar’s poetry as an assurance of divine care for man, and thus as an incentive to man to transcend his entrapment in the transience of the everyday moment.
Boris Šinigoj
doaj   +1 more source

Hieroglyphiskt i Stockholms slott omkring 1900

open access: yesICO Iconographisk Post, 2021
This paper deals with some themes composed by and for King Oskar II in the Royal Palace in Stockholm. Three paintings in the ceiling of the King’s staircase depict Society andSweden, the Cosmos and the Transfiguration. They
Bo Vahlne
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Can Twilight Become a Natural Therapy? An Examination of the Interpretation of QS. An-Nur Verse 35 from a Psychological Perspective

open access: yesQiST
This article examines the relationship between the twilight phenomenon and mental health through an interpretative study of the Qur'an, particularly Surah An-Nur verse 35.
Faza Aminaturroisah   +1 more
doaj   +1 more source

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