Results 51 to 60 of about 44,013 (215)

Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials

Advanced Science, EarlyView.
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang, Mengyu Li, Xiaohang Xie, Ao Chen, Thomas G. Bifano, Xin Zhang   +5 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Inhibition of renin-angiotensin system attenuates type I alveolar epithelial cell necroptosis in rats after hyperbaric hyperoxic exposure

Frontiers in Medicine
ObjectiveThere is evidence showing both necroptosis and activation of renin-angiotensin system (RAS) are involved in the pathogenesis of hyperbaric hyperoxic lung injury (HLI).
CuiHong Han, PeiXi Zhang, Ying Liu, JiaJun Xu, XuHua Yu, YuKun Wen, ShiFeng Wang, WenWu Liu   +7 more
doaj   +1 more source

Serum tau concentration after diving - an observational pilot study

, 2019
Increased concentrations of tau protein are associated with medical conditions involving the central nervous system, such as Alzheimer's disease, traumatic brain injury and hypoxia.
Sandstrom, Goran,, Seeman-Lodding, Helen,, Blennow, Kaj,, Kvarnström, Andreas, Zetterberg, Henrik,, Gennser, Mikael, Oscarsson, Nicklas,, Kvarnstrom, Andreas,, Gennser, Mikael,, Seeman-Lodding, Heléne,, Rosén, Anders,, Sandström, Göran   +11 more
core   +1 more source

Unlocking Long‐Lived Charge‐Separated State in Pentamethine Cyanine Based on Anionic Hofmeister Effect for Photodynamic Immunotherapy

Advanced Science, EarlyView.
Based on the anionic Hofmeister effect, a universal strategy of incorporation of stereo‐π anion BPh4− into a series of Cy5 skeletons to unlock long‐lived charge‐separated states was reported, wherein the weak electronic coupling and low charge recombination driving force hinder the charge recombination process, elevating the oxygen‐independent ROS ...
Xuan Zhao, Lei Jiang, Yingyong Ni, Ting Wang, Junjun Wang, Shengyu Shi, Jianhua Yu, Zhou Lu, Xiaojiao Zhu, Hongping Zhou   +9 more
wiley   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Risk of acute somatic hospital admissions among seafarers: a registry-based study in Norway

BMJ Open
Objectives To investigate whether seafarers in Norway who were declared unfit for service at sea or received a time-limited health certificate had a higher risk of acute somatic hospital admissions compared with those who received a full health ...
Stein Håkon Låstad Lygre, Jon Magnus Haga, Marit Grønning, Sahil Gulati   +3 more
doaj   +1 more source

THE PROCEDURE BY EVALUATION OF DIVERS FOR THE DEEP DIVING [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2014
When a diver is selected to perform a deep diving course, he has to pass a medical test and isn’t affected by the HPNS (High Pressure Nervous Syndrome). When a diver is selected to perform a deep diving course, he has to pass an evaluation stage in order
Mihai DIACONU, Tamara STANCIU, Mircea DEGERATU   +2 more
doaj  

The influence of scuba diving experience on divers' perceptions, and its implications for managing diving destinations.

PLoS ONE, 2019
Scuba diving experience-which can include accumulated diving experience and familiarity with a diving location-is an important descriptor of diver specialisation and behaviour.
Serena Lucrezi, Martina Milanese, Carlo Cerrano, Marco Palma   +3 more
doaj   +1 more source

Experimentally Determined Spatiotemporal Charge Carrier Dynamics for the Development of Particulate Photocatalysts

Advanced Energy Materials, EarlyView.
This review looks at the different experimental techniques that measure spatiotemporal charge carrier dynamics. This information is viewed in the context of particulate photocatalysts, outlining the insights these techniques provide and how they advance our understanding.
Sutripto Khasnabis, Robert Godin
wiley   +1 more source