Results 111 to 120 of about 887,804 (330)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The divisome is a self-enhancing machine in Escherichia coli and Caulobacter crescentus

Nature Communications
During bacterial cytokinesis, polymers of the bacterial tubulin FtsZ coalesce into the Z ring to orchestrate divisome assembly and septal cell wall synthesis.
Han Gong, Di Yan, Yuanyuan Cui, Ying Li, Jize Yang, Wenjie Yang, Rui Zhan, Qianqian Wan, Xinci Wang, Haofeng He, Xiangdong Chen, Joe Lutkenhaus, Xinxing Yang, Shishen Du   +13 more
doaj   +1 more source

Noncommutative symmetric functions and W-polynomials

, 2006
Let K,S,D be a division ring, an endomorphism and a S-derivation of K, respectively. In this setting we introduce generalized noncommutative symmetric functions and obtain Vieta formula and decompositions of differential operators.
Delenclos, J., Leroy, A.
core   +1 more source

Weierstrass division theorem in quasianalytic local rings [PDF]

, 2008
Abdelhafed Elkhadiri, Hassan Sfouli
openalex   +1 more source

Finite power-associative division rings [PDF]

Proceedings of the American Mathematical Society, 1966
The author proves the well-known theorem: ``A finite strictly power-associative division ring of characteristic \(\neq 2\) is a field'' without using the classification of central simple Jordan algebras, as in Albert's proof [cf. \textit{R. D. Schafer}, An introduction to nonassociative algebras. New York etc.: Academic Press (1966; Zbl 0145.25601), p.
openaire   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

The Kil peptide of bacteriophage λ blocks Escherichia coli cytokinesis via ZipA-dependent inhibition of FtsZ assembly.

PLoS Genetics, 2014
Assembly of the essential, tubulin-like FtsZ protein into a ring-shaped structure at the nascent division site determines the timing and position of cytokinesis in most bacteria and serves as a scaffold for recruitment of the cell division machinery ...
Daniel P Haeusser, Marina Hoashi, Anna Weaver, Nathan Brown, James Pan, James A Sawitzke, Lynn C Thomason, Donald L Court, William Margolin   +8 more
doaj   +1 more source

Containment-Division Rings and New Characterizations of Dedekind Domains [PDF]

, 2017
Danny A. J. Gómez–Ramírez, Juan D. Vélez, Edisson Gallego   +2 more
openalex   +1 more source

The q-division ring and its fixed rings

Journal of Algebra, 2014
Comment: Corrected a few minor ...
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source