Results 41 to 50 of about 313,688 (226)
MicrobTiSDA is a user‐friendly and flexible R package specifically designed for longitudinal microbiome data analysis. By integrating process‐oriented functional modules—including data input, data preprocessing, interspecies interaction inference, natural spline regression modeling, temporal pattern clustering, and random forest classification ...
Shijia Li +5 more
wiley +1 more source
Trisomy 21, or Down syndrome (DS), is a genetic disorder affecting approximately 1 in 500–750 live births. The prevalence of DS has increased over the past two decades, correlating with a rise in the proportion of pregnancies complicated by advanced ...
Diamond Ling, Jonathan G Dayan
doaj +1 more source
A nation-wide twin study of social cognition in schizophrenia spectrum disorders
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ).
Cecilie K. Lemvigh +2 more
doaj +1 more source
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson +5 more
wiley +1 more source
Twinning and birth defects: Rachipegal heteropagal twins and acardiac twins
Twin pregnancies are associated with multiple birth defects. The increase in twinning was attributed to fertility treatments. Twins were supposed to be associated with increased risk of congenital malformations.
Padmavathi Devi Chaganti +3 more
doaj +1 more source
Fathering of dizygotic twins and risk of prostate cancer: nationwide, population-based case-control study. [PDF]
BACKGROUND: An association between male fertility and risk of prostate cancer has been suggested, possibly through lower androgen levels in subfertile men.
Sara Wirén +4 more
doaj +1 more source
Abstract Background The cumulative effect of early medical events has been shown to be associated with autism. It is unclear whether this effect is specific to autism or if it is associated to other neurodevelopmental conditions (NDCs) as well. Methods We established a registry‐linked population‐based twin cohort of 10,254 pairs within the child and ...
Torkel Carlsson +4 more
wiley +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni +2 more
wiley +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source

