Results 71 to 80 of about 1,710,924 (336)

Effects of Dietary Supplementation with dl-Methionine and dl-Methionyl-dl-Methionine in Breeding Pigeons on the Carcass Characteristics, Meat Quality and Antioxidant Activity of Squabs

open access: yesAntioxidants, 2019
This study aimed to investigate the effects of dietary supplementation with dl-methionine (dl-Met) and dl-methionyl-dl-methionine (dl-Met-Met) in breeding pigeons on the carcass characteristics, meat quality and antioxidant activity of squabs. A total of
Shi-guang Jiang   +5 more
semanticscholar   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Tailoring temporal description logics for reasoning over temporal conceptual models [PDF]

open access: yes, 2011
Temporal data models have been used to describe how data can evolve in the context of temporal databases. Both the Extended Entity-Relationship (EER) model and the Unified Modelling Language (UML) have been temporally extended to design temporal ...
Ryzhikov, Vladislav   +8 more
core   +1 more source

Enhanced IDS with Deep Learning for IoT-Based Smart Cities Security

open access: yesTsinghua Science and Technology
Cyberattacks against highly integrated Internet of Things (IoT) servers, apps, and telecoms infrastructure are rapidly increasing when issues produced by IoT networks go unnoticed for an extended period.
Chaimae Hazman   +3 more
doaj   +1 more source

Customer Value Types Predicting Consumer Behavior at Dutch Grocery Retailers

open access: yesBehavioral Sciences, 2020
The purpose of this paper is to profile three grocery retail formats (non-discounter, soft discounter, and hard discounter) in the Netherlands using Holbrook’s value types.
Kim Janssens   +3 more
doaj   +1 more source

Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia and LDL-C of 160 mg/dl or Higher

open access: yesCardiovascular Drugs and Therapy, 2016
PurposeEven with statins and other lipid-lowering therapy (LLT), many patients with heterozygous familial hypercholesterolemia (heFH) continue to have elevated low-density lipoprotein cholesterol (LDL-C) levels. ODYSSEY HIGH FH (NCT01617655) assessed the
H. Ginsberg   +7 more
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Auto- and cross-regulation of the hnRNPs D and DL

open access: yesRNA: A publication of the RNA Society, 2018
HnRNP D, better known as AUF1, is an extensively studied protein that controls a variety of cellular pathways. Consequently, its expression has to be tightly regulated to prevent the onset of pathologies.
K. Kemmerer   +2 more
semanticscholar   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

dl;dl-mVenus [PDF]

open access: yes, 2017
All lsm files (images taken with a Zeiss 710) of dl;dl-mVenus embryos used in the analysis (quantitative or qualitative) in this paper.
Amy E. Allen (5011622)   +11 more
core   +1 more source

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