Results 11 to 20 of about 52,371 (280)
Cardiac Involvement by HIV-Associated DLBCL [PDF]
Non-Hodgkin’s lymphoma (NHL) is a common AIDS-defining malignancy among people living with HIV. Of the different types of NHLs, diffuse large B-cell lymphoma (DLBCL) is the most common. Prognosis of DLBCL has improved over the years in the general population but remains relatively poor in HIV-positive individuals.
Charles T. Mupamombe +3 more
openaire +4 more sources
S1PR2 deficiency in DLBCL: a FOXy connection [PDF]
Inactivating mutations in the sphingosine-1-phosphate (S1P) receptor 2 (S1PR2) promoter have been associated with the germinal center (GC) B-cell diffuse large B-cell lymphoma (GCB-DLBCL) subtype. In this issue of Blood, Flori et al have now identified S1PR2 as a tumor suppressor that is transcriptionally silenced by forkhead box protein 1 (FOXP1) in ...
Baldari, Cosima
openaire +5 more sources
Transformed Lymphoma Is Associated with a Favorable Response to CAR-T-Cell Treatment in DLBCL Patients [PDF]
(1) Background: CAR-T-cell therapy is a novel therapeutic option for patients with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL).
Urban Novak +15 more
core +2 more sources
Predicting the future for DLBCL [PDF]
In this month’s CME article, Vercellino and colleagues report results of a secondary analysis of diffuse large B-cell lymphoma patients in the REMARC trial who had baseline positron emission tomography scans, thereby demonstrating that metabolic tumor volume combined with performance status allowed risk stratification of patients before treatment and ...
openaire +2 more sources
MYC is a potent oncogene that encodes a transcription factor which regulates a plethora of target genes related to cell growth and cell cycle. Not surprisingly, a vast majority of human cancers are characterized by high constitutive Myc levels promoting oncogenesis.
Itziar, Salaverria, Sílvia, Beà
openaire +2 more sources
A Novel Plasma Biomarker hsa_circ_0080018 Drives DLBCL Progression via M2 Polarization of Tumor‐Associated Macrophages [PDF]
The proposed mechanistic model in this study. ABSTRACT Noncoding RNAs, including circular RNAs (circRNAs), have been demonstrated to play vital roles in tumorigenesis. Uncovering the functions of circRNAs in tumorigenesis and their underlying regulatory mechanisms may suggest new approaches to the development of novel diagnostic and therapeutic ...
Liu Y, Gao Y, Zhao C.
europepmc +2 more sources
Epstein-Barr virus positive DLBCL, NOS (EBV + DLBCL, NOS) occurs in apparently immunocompetent patients usually older than 50 years, which can also occur in younger patients and has a worse prognosis than EBV negative tumors.
Chen, Ding-Bao
core +1 more source
A lumpy bumpy stomach: The more the murkier
This report describes the radiological and endoscopic findings in a 54-year-old male who presented with epigastric pain. The patient underwent an upper gastrointestinal (GI) barium study followed by axial imaging, which demonstrated nodular gastric wall ...
Binit Sureka +5 more
doaj +1 more source
Plasma extracellular vesicles (EVs) have been reported to be a promising source of diagnostic and prognostic biomarkers in various cancers. However, further research in this area is needed due to the limitations of circulating extracellular vesicles ...
Ji-Wei Li +10 more
doaj +1 more source
Primary Paratesticular Lymphoma with Testicular Sparing: Account of an Unusual Scrotal Mass [PDF]
Tumours of the testicular adnexa include a heterogeous group of mesothelial, mesenchymal and germ cell tumours. Adenomatoid tumour, pseudosarcomatous myofibroblastic proliferations and rhabdomyosarcoma are the more frequently encountered neoplasms ...
Vidya Monappa +2 more
doaj +1 more source

