Varnimcabtagene autoleucel (ARI‐0001) in relapsed or refractory mantle cell lymphoma
Abstract Varnimcabtagene autoleucel (var‐cel) is an autologous CD19‐directed chimeric antigen receptor (CAR) T‐cell therapy administered using an adaptive, fractionated dosing strategy. We conducted a multicenter retrospective study to evaluate the safety and efficacy of var‐cel in patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL ...
Nil Albiol +41 more
wiley +1 more source
rTCT: Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration
ABSTRACT Path integration is navigation in the absence of environmental landmarks and is a primary cognitive mechanism underlying spatial memory. Path integration performance is primarily assessed in humans using the Triangle Completion Task (TCT). In humans, TCT has shown promise for the early diagnosis of Alzheimer's disease.
Stephen Duncan +13 more
wiley +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Silver-Doped Diamond-Like Carbon Coatings on Ti<sub>6</sub>Al<sub>4</sub>V Alloy with Enhanced Antibacterial and Cytocompatible Properties. [PDF]
Reim Del' Gaudio Pignataro R +7 more
europepmc +1 more source
IBD is driven by a vicious cycle of dysbiosis, barrier dysfunction, and immune dysregulation. We developed an inulin–butyrate conjugate nanogel (IBN) that accumulates in inflamed colon and releases butyrate via microbial inulinase/esterase. The inulin shell remodels the microbiome, while localized butyrate strengthens barrier integrity and promotes ...
Nayoon Park +7 more
wiley +1 more source
Advances in Doping Modification and Processing of Diamond-like Carbon Coatings: A Review. [PDF]
Zhang Z +4 more
europepmc +1 more source
This study demonstrates tunable photovoltaic responses in pure, polycrystalline BiFeO3 thin films, controlled by external electric and magnetic fields. By aligning ferroelectric domains and leveraging magnetoelectric coupling, the photogeneration is amplified up to seven times.
Luciano Cardoso Dias +14 more
wiley +1 more source
Bounding the costs of electric vehicle managed charging-supply curves for scenarios from 2025 to 2050. [PDF]
Matsuda-Dunn R +4 more
europepmc +1 more source
Wind Turbine Model Validation Is Improved by High‐Resolution, Measurement‐Derived Inflows
ABSTRACT There is an increased need for accurate validation of turbine models used by original equipment manufacturers to fine‐tune prototypes and predict power performance and maintenance needs while avoiding costly warranty payouts. Perhaps the most substantial source of uncertainty in typical wind turbine model validation procedures is the use of ...
Daniel Houck +6 more
wiley +1 more source

