Results 111 to 120 of about 212,022 (284)

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Development of a Model and Designing a System for Water Purification from Hydrocarbons

Journal of Sustainable Development of Energy, Water and Environment Systems
This paper presents a model based on which the system for purifying water from hydrocarbons was designed with an acceptable flow and water quality for discharge into surface waters.
Igor Meixner, Lovorka Gotal Dmitrovic, Jan Meixner   +2 more
doaj   +1 more source

Layer-by-Layer Biopolymer-Coated Deformable Liposomes–In Situ Gel: A Hybrid Strategy for Enhanced Ocular Delivery of Itraconazole: In Vitro and In Vivo Appraisal

Gels
Itraconazole (ITZ) is a potent antifungal agent. Its oral administration is associated with systemic toxicity, and its efficacy in ocular formulations is limited.
Mohamed M. Badran, Areej Alsubaie, Mounir M. Salem Bekhit, Abdullah H. Alomrani, Aliyah Almomen   +4 more
doaj   +1 more source

Degenerative Left Shift as a Prognostic Tool in Cats

Journal of Veterinary Internal Medicine, 2014
Background A degenerative left shift (DLS) is reported to be a poor prognostic indicator in dogs and cats. Limited data in dogs and no studies in cats have been published to investigate this claim.
A.G. Burton, L.A. Harris, S.D. Owens, K.E. Jandrey   +3 more
doaj   +1 more source

MSFC Doppler Lidar Science experiments and operations plans for 1981 airborne test flight [PDF]

The flight experiment and operations plans for the Doppler Lidar System (DLS) are provided. Application of DLS to the study of severe storms and local weather penomena is addressed. Test plans involve 66 hours of flight time.
Bilbro, J. W., Fichtl, G. H., Kaufman, J. W.   +2 more
core   +1 more source

Introduction : user studies for digital library development [PDF]

, 2012
Introductory chapter to the edited collection on user studies in digital library development.
Dobreva, Milena, Feliciati, Pierluigi, O'Dwyer, Andy   +2 more
core  

Emergent Spin‐Glass Behavior in an Iron(II)‐Based Metal–Organic Framework Glass

Advanced Functional Materials, EarlyView.
A one‐pot, solvent‐free synthesis yields an Fe2+‐based metal‐organic framework (MOF) glass featuring a continuous random network structure. The material exhibits spin‐glass freezing at 14 K, driven by topological‐disorder and short‐range magnetic frustration, showcasing the potential of MOF glasses as a plattform for cooperative magnetic phenomena in ...
Chinmoy Das, Soma Salamon, Joachim Landers, Jan‐Benedikt Weiß, Wen‐Long Xue, Pascal Kolodzeiski, Roman Pallach, Heiko Wende, Sebastian Henke   +8 more
wiley   +1 more source

Is it time to define vaccines to be used for lumpy skin disease?

Health Sciences Review
Only homologous LSD vaccine should be used in absence of efficacy of experimental studies indicating the effectiveness of heterologous LSD vaccine.
Krishna Prasad Acharya, Bhoj Raj Singh
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Insight into the Internal Structure of Biogenic, Synthetic and Geological Apatite by Electron Microscopy and X‐Ray Scattering

Advanced Functional Materials, EarlyView.
Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka, Oleg Prymak, Kateryna Loza, Matthias Epple   +3 more
wiley   +1 more source