Results 61 to 70 of about 39,022 (246)

One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy

Advanced Science, EarlyView.
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu, Ben Huang, Lingyan Wang, Qiang Guo, Cuiping Jiang, Ruicheng Qi, Shuyao Wang, Lin‐Tai Da, Wenjie Peng   +8 more
wiley   +1 more source

Fairness Notions in DAG-Based DLTs

2023 5th Conference on Blockchain Research & Applications for Innovative Networks and Services (BRAINS), 2023
This paper investigates the issue of fairness in Distributed Ledger Technology (DLT), specifically focusing on the shortcomings observed in current blockchain systems due to Miner Extractable Value (MEV) phenomena and systemic centralization. We explore the potential of Directed Acyclic Graphs (DAGs) as a solution to address or mitigate these fairness ...
Raikwar, Mayank, Polyanskii, Nikita, Müller, Sebastian   +2 more
openaire   +2 more sources

G4‐Ligand‐Directed PROTACs Unveil DR1 as a Novel Ligand‐Co‐Binding G4‐Protein and Reshape G4‐Dependent Transcription

Advanced Science, EarlyView.
G4‐binding proteins (G4BPs) that specifically co‐bind G4s in the presence of small‐molecule ligands represent a critical but unexplored class of proteins. We introduce G4‐Ligand‐Directed PROTACs (G4L‐TACs), a chemical platform that couples G4 ligands (PDS) to E3 recruiters to selectively degrade these ligand‐co‐binding G4BPs.
Mao‐Lin Li, Shu‐Min Xu, Xin‐Chen Jiang, Le‐Tian Dai, Yu‐Tao Hu, Kai‐Bo Wang, Jia‐Heng Tan, Zhi‐Shu Huang, Shuo‐Bin Chen   +8 more
wiley   +1 more source

Effect of intubation in lateral position on placement of a double-lumen tube in patients undergoing unilateral video-assisted thoracic surgery: a randomied clinical trialResearch in context

EClinicalMedicine
Summary: Background: Approximately one-third of patients who undergo double-lumen tube (DLT) intubation in the conventional supine position experience DLT malposition. No randomized study investigates the effect of DLT intubation in the lateral position.
Xi Zhang, Dongxu Wang, Zhenduo Zhang, Yawen Tang, Qin Zhang, Fei Tong, Yonghe Hu, Xian Lu, He Liu, Siping Hu   +9 more
doaj   +1 more source

Comparison of displacement of polyvinyl chloride and silicone left-sided double-lumen tubes during lateral positioning [PDF]

Korean Journal of Anesthesiology, 2019
Background Compared to an equivalent sized polyvinyl chloride (PVC) double-lumen tube (DLT), a silicone DLT has a shorter endobronchial segment. The aim of this study was to compare the incidence of clinically significant displacement of left-sided PVC ...
Nyeong Keon Kwon, Sung Mee Jung, Sang-Jin Park, Yonghee Han   +3 more
doaj   +1 more source

Distributed Ledger Technology (DLT) and blockchain

, 2017
The financial sector is currently undergoing a major transformation, brought about by the rapid development and spread of new technologies. The confluence of 'finance' and 'technology' is often referred to as 'Fintech', typically describing companies or ...
H. Natarajan, S. Krause, H. L. Gradstein
semanticscholar   +1 more source

DL-Tags: DLT and Smart Tags for Decentralized, Privacy-Preserving, and Verifiable Supply Chain Management

IEEE Access, 2019
Supply chain management enhanced by the Internet of Things (IoT) solutions integrate special tags (e.g., RFID, NFC, and QR-codes) with products to create Smart Tags, in addition to storing supplemental information about a product, which is also used to ...
Federico Matteo Benčić, Pavle Skočir, Ivana Podnar Žarko   +2 more
semanticscholar   +1 more source

OsGSK2‐OsTCP19 Module Integrates Nitrogen and Brassinosteroid Signaling to Regulate Nitrogen Utilization and Root Growth in Rice

Advanced Science, EarlyView.
OsGSK2‐OsTCP19 module regulating nitrate response and lateral root (LR) development. Low‐nitrate condition results in reduced BR response, accumulation of OsGSK2 and phosphorylated OsTCP19, which suppresses the expression of nitrate‐responsive genes and LR‐development genes and impairs rice growth.
Yongqiang Liu, Weiwei Li, Xiaohui Ma, Xiaohan Wang, Yarong Shi, Xiahe Huang, Xinran Li, Yingchun Wang, Hongning Tong, Bin Hu, Wenbin Zhou, Chengcai Chu   +11 more
wiley   +1 more source

Selective Ion‐Blocking Strategy for Stabilizing Perovskite Tandem Solar Cells

Advanced Energy Materials, EarlyView.
A selective ion‐blocking Li─T interlayer is introduced at LiF‐passivated perovskite interfaces to suppress fluorine diffusion while preserving the beneficial interfacial passivation of LiF. This ion‐blocking strategy markedly improves the long‐term operational stability of both single‐junction and monolithic all‐perovskite tandem cells under continuous
Sunwoo Kim, Hangyeol Choi, Doyun Im, Yeonghun Yun, Won Chang Choi, Jungchul Yun, Hyun Seo Park, Nagyeong Hyeon, Dong Hyun Kim, Gill Sang Han, Junesic Park, Gwang Min Sun, Jun Hong Noh, Ji‐Sang Park, Yohan Yoon, Sangwook Lee   +15 more
wiley   +1 more source

SCANNING-DLTS

Le Journal de Physique Colloques, 1989
Scanning Deep Level Transient Spectroscopy (SDLTS) is a current SEM technique for the detection of the local distribution of deep level centres in semiconductors. The contribution deals with the physical foundations of the SDLTS technique and it discusses the demands on the instrumentation.
openaire   +2 more sources