Results 81 to 90 of about 16,572 (218)
INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan +13 more
wiley +1 more source
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe +5 more
wiley +1 more source
The Landless Rural Workers Movement (MST) and New Agrarian Questions in Brazil
ABSTRACT The Landless Rural Workers Movement of Brazil (MST) primarily organized occupations of large‐scale farms, forcing the redistribution of land for creation of agrarian reform settlements. In the past 20 years, however, land occupations and the establishment of new agrarian reform settlements have consistently declined, while the MST shifted ...
Estevan Coca, Gustavo de L. T. Oliveira
wiley +1 more source
Introduction Lung isolation is primarily accomplished using a double-lumen tube (DLT) or bronchial blocker. A precise and accurate size of the DLT is a prerequisite for ensuring its accurate placement. Three-dimensional (3D) reconstruction technology can
Yi Xu +11 more
doaj +1 more source
Abstract This study investigated which type of Mandarin Chinese relative clause (RC)—subject‐extracted relative clause (SRC) or object‐extracted relative clause (ORC)—imposes greater processing demands on second language (L2) learners’ production. Sixty‐two native (L1) Mandarin speakers and 72 L1 Korean learners of Mandarin participated in a picture ...
Deran Kong, Sun‐A Kim, Jeong‐Ah Shin
wiley +1 more source
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal +29 more
wiley +1 more source
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt +8 more
wiley +1 more source
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley +1 more source
Dowel-laminated timber (DLT) is a composite structural material manufactured entirely from wood. Increasing awareness of the sustainability, end-of-life recyclability, and potential health concerns associated with synthetic adhesives used in cross ...
Benjamin Higgins +5 more
doaj +1 more source
O2 verbessert den Ladungstransfer in organischen n‐Typ‐Donor‐Akzeptor‐Ladungstransferkomplexen (CTCs) durch physisorptive Passivierung von Ladungsträgerfallen. Durch die Unterdrückung der Rekombination und die Förderung langlebiger delokalisierter Ladungsträger verbessert O2 den Elektronentransport und die Leitfähigkeit ohne Dotierung.
Kirill K. Gubanov +16 more
wiley +1 more source

