Results 81 to 90 of about 16,572 (218)

INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol

open access: yesBJU International, EarlyView.
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan   +13 more
wiley   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

open access: yesCancer Science, EarlyView.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe   +5 more
wiley   +1 more source

The Landless Rural Workers Movement (MST) and New Agrarian Questions in Brazil

open access: yesJournal of Agrarian Change, EarlyView.
ABSTRACT The Landless Rural Workers Movement of Brazil (MST) primarily organized occupations of large‐scale farms, forcing the redistribution of land for creation of agrarian reform settlements. In the past 20 years, however, land occupations and the establishment of new agrarian reform settlements have consistently declined, while the MST shifted ...
Estevan Coca, Gustavo de L. T. Oliveira
wiley   +1 more source

Effect of a 3D-printed reconstruction automated matching system for selecting the size of a left double-lumen tube: a study protocol for a prospective randomised controlled trial

open access: yesBMJ Open
Introduction Lung isolation is primarily accomplished using a double-lumen tube (DLT) or bronchial blocker. A precise and accurate size of the DLT is a prerequisite for ensuring its accurate placement. Three-dimensional (3D) reconstruction technology can
Yi Xu   +11 more
doaj   +1 more source

Mandarin Relative Clause Production by Second Language Learners: Subject–Object Asymmetry and Individual Differences

open access: yesLanguage Learning, EarlyView.
Abstract This study investigated which type of Mandarin Chinese relative clause (RC)—subject‐extracted relative clause (SRC) or object‐extracted relative clause (ORC)—imposes greater processing demands on second language (L2) learners’ production. Sixty‐two native (L1) Mandarin speakers and 72 L1 Korean learners of Mandarin participated in a picture ...
Deran Kong, Sun‐A Kim, Jeong‐Ah Shin
wiley   +1 more source

Quizartinib in Combination With FLAG‐IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG‐QUIDA): A PETHEMA Phase I‐II Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2258-2268, September 2026.
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal   +29 more
wiley   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2288-2296, September 2026.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt   +8 more
wiley   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

A Linear-Elastic Numerical Method and Optimisation Strategies for Dowel-Laminated Timber in Australia

open access: yesApplied Sciences
Dowel-laminated timber (DLT) is a composite structural material manufactured entirely from wood. Increasing awareness of the sustainability, end-of-life recyclability, and potential health concerns associated with synthetic adhesives used in cross ...
Benjamin Higgins   +5 more
doaj   +1 more source

Passivierung von Defektzuständen in organischen n‐Typ‐Ladungstransferkomplexen durch molekularen Sauerstoff

open access: yesAngewandte Chemie, Volume 138, Issue 33, 10 August 2026.
O2 verbessert den Ladungstransfer in organischen n‐Typ‐Donor‐Akzeptor‐Ladungstransferkomplexen (CTCs) durch physisorptive Passivierung von Ladungsträgerfallen. Durch die Unterdrückung der Rekombination und die Förderung langlebiger delokalisierter Ladungsträger verbessert O2 den Elektronentransport und die Leitfähigkeit ohne Dotierung.
Kirill K. Gubanov   +16 more
wiley   +1 more source

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