Results 91 to 100 of about 16,572 (218)

Molecular Dioxygen‐Mediated Passivation of Electron Traps in n‐Type Organic Charge‐Transfer Complexes

Angewandte Chemie International Edition, Volume 65, Issue 33, 10 August 2026.
O2 enhances charge‐transfer in n‐type organic donor–acceptor charge‐transfer complexes (CTCs) via physisorption‐mediated trap passivation. By suppressing recombination and promoting long‐lived delocalized charge carriers, O2 improves electron transport and conductivity without doping.
Kirill K. Gubanov, Yana Reva, Christian L. Ritterhoff, Fabio Candolfi, Daniel Langford, Maximilian Herm, Evanie Franz, Ryan W. Crisp, Frank Hampel, Michael Krieger, Andreas Späth, Benjamin Watts, Jörg Libuda, Heiko B. Weber, Bernd Meyer, Dirk M. Guldi, Rainer H. Fink   +16 more
wiley   +1 more source

Spatial Strategies in Coral Transplantation: A Systematic Review of Clustered Versus Widespread Configurations

Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 8, August 2026.
ABSTRACT Active coral reef restoration incorporates ecological engineering principles. Yet, the spatial arrangement of transplanted colonies, one of the few design parameters directly controlled by practitioners, remains poorly explored empirically. We conducted a systematic review following PRISMA guidelines to evaluate how clustered (high‐density ...
Dor Shefy, Giovanni Giallongo, Ana De La Torriente Diez, Sergio Rossi   +3 more
wiley   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2764-2776, August 2026.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source

Vobramitamab duocarmazine, an anti–B7‐H3 antibody–drug conjugate, in patients with advanced solid tumors: Final results of a phase 1 cohort expansion

Cancer, Volume 132, Issue 15, 1 August 2026.
Abstract Background Vobramitamab duocarmazine is an investigational antibody–drug conjugate (ADC) targeting B7 homolog 3 (B7‐H3) with a cytotoxic duocarmycin‐based DNA‐alkylating payload. This study evaluated its safety and antitumor activity in advanced solid tumors.
Eugene Shenderov, Manish R. Sharma, Elena Garralda, John Powderly, Iwona Ługowska, Alexander Spira, Marc Cucurull Salamero, Sekwon Jang, Rasha Cosman, John Shen, Wen Xu, Piotr J. Wysocki, Rodryg Ramlau, Emmanuel S. Antonarakis, Andrew J. Weickhardt, Jakub Żołnierek, Emiliano Calvo, Enxu Zhao, Chet Bohac, Ashley Ward, Girish Mallesara   +20 more
wiley   +1 more source

Evaluating the precision of ultrasound versus computed tomography-guided measurement of cricoid cartilage diameter for double-lumen tube selection in thoracic surgery: A randomised comparative study

Indian Journal of Anaesthesia
Background and Aims: Precise airway management is vital in thoracic surgeries to ensure patient safety and optimal outcomes. Choosing the correct double-lumen tube (DLT) size is challenging, as it typically relies on height, gender and subjective ...
Roshni M. Mathew, Shefali Gautam, Rajesh Raman, Anurag Rai, Vinod K. Srivastava, Manish K. Singh   +5 more
doaj   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Quantifying Multidimensional Effects in Linear Site Response Using 1D and 2D Simulations of Sedimentary Basins in Wellington, New Zealand

Earthquake Spectra, Volume 42, Issue 3, August 2026.
This study quantifies the influence of multidimensional effects on site response in the Wellington region of New Zealand by comparing results from different simulation approaches. Response‐spectral amplification functions from 1D and 2D site response analyses are compared to quantify the magnitude and spatial distribution of multidimensional effects ...
Christopher A. de la Torre, Christopher R. McGann, Brendon A. Bradley, Matthew Hill   +3 more
wiley   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao, Yun Liang, Xinwen Liang, Qisheng Su, Xiaohong Li   +4 more
wiley   +1 more source

3D Electrical Impedance Tomography of Regional Ventilation During Jet Ventilation: A Pilot Study

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Objectives Low‐frequency jet ventilation (LFJV) is commonly used in laryngotracheal surgery when intubation is not feasible. However, limited understanding of regional ventilation and distal airway pressures raises safety concerns and restricts broader adoption.
Daniel S. Fink, Nilton Barbosa da Rosa Jr, Sanghee Cho, Michelle Mellenthin, Andre Vieira Pigatto, Tzu‐Jen Kao, Benjamin Cloyd, Ana Fernandez‐Bustamante, Matthew Clary, Drew Gottman, Ryan Lau, Jennifer L. Mueller   +11 more
wiley   +1 more source