Results 91 to 100 of about 22,979 (272)

Safe Artificial General Intelligence via Distributed Ledger Technology

open access: yesBig Data and Cognitive Computing, 2019
Artificial general intelligence (AGI) progression metrics indicate AGI will occur within decades. No proof exists that AGI will benefit humans and not harm or eliminate humans.
Kristen W. Carlson
doaj   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

open access: yesElectron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary   +5 more
wiley   +1 more source

Dose-limiting toxicity (DLT) according to SMM status.

open access: yes, 2023
Dose-limiting toxicity (DLT) according to SMM status.
Jan-Niklas Becker (14659860)   +5 more
core   +1 more source

Non‐fullerene acceptor aggregation regulation via additives dipole moment leads to 19.9% power conversion efficiency in bilayer organic solar cells

open access: yesFlexMat, EarlyView.
Additives interact with non‐fullerene acceptors to modulate their aggregation behavior and molecular orientation via optimizing crystallization kinetics. The optimized morphology effectively suppresses charge carrier recombination and enhances charge transport. Notably, 2‐chloro‐1,3‐dibromobenzene with the dipole moments of 2.56 D enables the PM6/L8‐BO
Jingjing Zhao   +8 more
wiley   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang   +10 more
wiley   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson   +10 more
wiley   +1 more source

DLT-based trading venues and EU capital markets legislation: state of the art and perspectives under the DLT pilot regime [PDF]

open access: yes, 2023
This paper aims to analyze the interconnection of the recently published DLT Regulation with traditional pieces of EU financial legislation, particularly MiFID II and the CSDR, as to the treatment of market infrastructures. Therefore, the study’s main
Annunziata, Filippo   +2 more
core  

BPM and Process Performance: A Bibliometric Synthesis, Cases, and Research Agenda Anchored in the SDGs

open access: yesKnowledge and Process Management, EarlyView.
ABSTRACT This study reviews BPM literature, examining how research conceptualizes and reports the relationship between BPM, performance, and sustainability, key trends, gaps, and future directions, combining bibliometric analysis with previously published case studies to connect theory and practice for organizational optimization.
Julio Gumiero   +2 more
wiley   +1 more source

Subglottic Stenosis After Double‐Lumen Tube Intubation With Reintubation: A Case Report and Review of Japanese Cases

open access: yesClinical Case Reports
Subglottic stenosis after double‐lumen tube (DLT) intubation is more likely to occur when an oversized DLT, specifically a 35 Fr DLT, is used in older, shorter women. Reintubation in such cases is challenging and may cause additional traumatic laryngitis.
Masami Suzuki, Naohiro Yoshida
doaj   +1 more source

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP-00). [PDF]

open access: yesProstate
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
King LD   +8 more
europepmc   +2 more sources

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