Results 101 to 110 of about 16,572 (218)
Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge +5 more
wiley +1 more source
ABSTRACT Purpose The clinical feasibility and translation of many advanced quantitative MRI (qMRI) techniques are inhibited by their restriction to ‘research mode’, due to resource‐intensive, offline parameter estimation. This work aimed to achieve ‘clinical mode’ qMRI, by real‐time, inline parameter estimation with a trained neural network (NN) fully ...
Samuel Rot +13 more
wiley +1 more source
Programmable van der Waals Heterojunction for Multifunctional Integration
A MoS2/MAPbBr3 van der Waals heterostructure is programmed by gate bias to switch among photodetector, synaptic transistor, and gate‐bias‐assisted optical‐memory modes. Gate‐controlled carrier trapping tunes the response timescale, enabling mode reconfiguration in a single device.
An Gui +9 more
wiley +1 more source
ABSTRACT Objectives Human islets are widely researched to understand pathophysiological mechanisms leading to diabetes. Sex, age, and body mass index (BMI) are key donor traits influencing islet function, which is also regulated by an intricate network of microRNAs.
Wilson K. M. Wong +18 more
wiley +1 more source
Coaxial Placement of Fogarty Catheter: A Simple Remedy for Incomplete Lung Isolation with DLT
Thoracic surgery requires lung isolation which is usually achieved by placing a double lumen tube (DLT). Correct placement of DLT is crucial for lung isolation. In this case report incomplete lung isolation with DLT was corrected using a Fogarty catheter
Amit Kumar Mittal +4 more
doaj
The dose escalation part of the first‐in‐human study of E7130 in patients with advanced solid tumors determined the Recommended Phase 2 Dose of E7130 (480 μg/m2 Q3W). The dose expansion part (presented here) examined safety/preliminary efficacy in patients with squamous cell carcinoma of the head and neck and urothelial carcinoma.
Nobuaki Matsubara +15 more
wiley +1 more source
Double-lumen tube (DLT) intubation is frequently performed for thoracic surgery, and a fiberoptic bronchoscopy (FOB) can improve the success rate of correct placement.
Wencai Jiang +7 more
doaj +1 more source
This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre +13 more
wiley +1 more source
ABSTRACT Rooted in the theoretical perspective of impression management, and drawing on the critical discourse analysis (CDA) approach, this study analyzes whether and how the Italian state‐owned enterprises (SOEs) in the energy sector over the period 2020–2023 use persuasive language strategies in their annual reports to portray the image of a ...
Fiorenza Meucci +3 more
wiley +1 more source
Xu (2016) defines the dlt motivic zeta function associated to a regular function f on a smooth variety X over a field of characteristic zero.This is an adaptation of the classical motivic zeta function that was introduced by Denef and Loeser (1998).
openaire +1 more source

