Results 101 to 110 of about 130,419 (249)

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations

Nucleic Acids Research, 2016
Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle-wasting disorder caused by mutations in the 2.4 Mb dystrophin-encoding DMD gene. The integration of gene delivery and gene editing technologies based on viral vectors and sequence-specific ...
I. Maggio, L. Stefanucci, J. Janssen, Jin Liu, Xiaoyu Chen, V. Mouly, M. Gonçalves   +6 more
semanticscholar   +1 more source

Measuring of customer satisfaction on example of Delta DMD [PDF]

Marketing (Beograd. 1991), 2010
Companies which do business in today's competitive environment, has to continuously work on improvement of theirs products and services, based on customers' needs.
Kostić Ela
doaj  

Sparse Sensing and DMD-Based Identification of Flow Regimes and Bifurcations in Complex Flows [PDF]

SIAM Journal on Applied Dynamical Systems, 2015
We present a sparse sensing framework based on dynamic mode decomposition (DMD) to identify flow regimes and bifurcations in large-scale thermofluid systems. Motivated by real-time sensing and control of thermal-fluid flows in buildings and equipment, we
B. Kramer, P. Grover, P. Boufounos, S. Nabi, M. Benosman   +4 more
semanticscholar   +1 more source

Predictors for the Longevity of People with Diabetes in Buno Bedele and Illubabor Zones, South-west Ethiopia

Diabetes, Metabolic Syndrome and Obesity, 2023
Melaku Tadege,1 Azmeraw Misganaw,2 Zemenay Truneh,1 Awoke Seyoum Tegegne3 1Department of Statistics, Injibara University, Injibara, Amhara, Ethiopia; 2Department of Statistics, Mettu University, Mettu, Oromia, Ethiopia; 3Department of Bio-Statistics ...
Tadege M, Misganaw A, Truneh Z, Tegegne AS   +3 more
doaj  

A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20

Skeletal Muscle, 2018
Boys with Duchenne muscular dystrophy (DMD) have DMD gene mutations, with associated loss of the dystrophin protein and progressive muscle degeneration and weakness. Corticosteroids and palliative support are currently the best treatment options.
Sara Mata López, James J. Hammond, Madison B. Rigsby, Cynthia J. Balog-Alvarez, J. Kornegay, P. P. Nghiem   +5 more
semanticscholar   +1 more source

Children with severe early childhood caries: streptococci genetic strains within carious and white spot lesions

Journal of Oral Microbiology, 2014
Background and objectives: Mutans streptococci (MS) are one of the major microbiological determinants of dental caries. The objectives of this study are to identify distinct MS and non-MS streptococci strains that are located at carious sites and non ...
Kenneth Gilbert, Raphael Joseph, Alex Vo, Trusha Patel, Samiya Chaudhry, Uyen Nguyen, Amy Trevor, Erica Robinson, Margaret Campbell, John McLennan, Farielle Houran, Tristan Wong, Kendra Flann, Melissa Wages, Elizabeth A. Palmer, John Peterson, John Engle, Tom Maier, Curtis A. Machida   +18 more
doaj   +1 more source

Porcine Zygote Injection with Cas9/sgRNA Results in DMD-Modified Pig with Muscle Dystrophy

International Journal of Molecular Sciences, 2016
Dystrophinopathy, including Duchenne muscle dystrophy (DMD) and Becker muscle dystrophy (BMD) is an incurable X-linked hereditary muscle dystrophy caused by a mutation in the DMD gene in coding dystrophin.
Honghao Yu, Heng Zhao, Yubo Qing, Weirong Pan, Baolin Jia, Hong-Ye Zhao, Xingxv Huang, Hongjiang Wei   +7 more
semanticscholar   +1 more source

Management of Severely Atrophic Maxilla in Ectrodactyly Ectodermal Dysplasia-cleft Syndrome

Plastic and Reconstructive Surgery, Global Open, 2018
Background:. Ectrodactyly ectodermal dysplasia-cleft syndrome is a rare genetic syndrome with an incidence of 1/90,000 live births, characterized by cleft lip and palate, severely hypoplastic maxilla, and hypodontia.
Adi Rachmiel, DMD, PhD, Shahar Turgeman, DMD, Omri Emodi, DMD, Dror Aizenbud, DMD, Dekel Shilo, DMD, PhD   +4 more
doaj   +1 more source

Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells

Scientific Reports, 2016
Mutations disrupting the reading frame of the ~2.4 Mb dystrophin-encoding DMD gene cause a fatal X-linked muscle-wasting disorder called Duchenne muscular dystrophy (DMD).
I. Maggio, Jin Liu, J. Janssen, Xiaoyu Chen, M. Gonçalves   +4 more
semanticscholar   +1 more source

Tele-Rehabilitation for Boys with Duchenne Muscular Dystrophy in India Amidst the COVID-19 Pandemic: An Implementation Study

International Journal of Disabilities Sports and Health Sciences
Purpose: Duchenne muscular dystrophy (DMD) is X-linked progressive neuromuscular disorder of childhood onset which leads to loss of ambulation, followed by respiratory and cardiac muscle weakness.
Amrit Pal Singh Sood, Seveka Bali, Somya Saxena, Sudhansu Baral, Ruby Nimesh, Renu Suthar, Priyanka Gupta   +6 more
doaj   +1 more source