Results 121 to 130 of about 60,875 (277)

GDF5 therapeutic potential for DMD

, 2021
International audienceDuchenne muscular dystrophy (DMD) is a lethal disorder characterized by the lack of dystrophin, which is essential for muscle fibers integrity as its absence results in muscle necrosis followed by cyclic degeneration and ...
Vergnol, Amélie, Giordani, Lorenzo, Forand, Anne, Saillard, Lucile, Piétri-Rouxel, France, Cadot, Bruno, Falcone, Sestina, Gentil, Christel, Noviello, Chiara, Meunier, Pierre   +9 more
core   +1 more source

Spectrum and cumulative events of 64 DMD deletion cases and 16 DMD duplication cases.

, 2014
DMD mutations were detected using MLPA. The X-axis represents exon position, and the Y-axis represents the percentage of the exons involved in deletion (blue) or duplication (pink).
Shusen Wang (433515), Xue Zhang (166886), Feng Zhang (6548), Hongwei Ma (290896), Yang Luo (350920), Chen Chen (6544), Xuesha Xing (632375), Lu Chen (75170)   +7 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Developing a Suitable Anion Exchange Layer Structure for Pure–Water Fed Bipolar Membrane CO2 Electrolysis

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A porous anion exchange layer (AEL) is implemented in a forward‐biased bipolar membrane CO2 electrolyzer to suppress carbonate crossover, support CO2 regeneration and maintain cathode alkalinity. Two fabrication strategies are compared—deposition on a silver gas diffusion electrode (GDE) or on the CEM—showing that a porous AEL‐coated GDE provides the ...
Henning Lorenz, Nico Roubicek, Simon Thiele, Chuyen van Pham   +3 more
wiley   +1 more source

Challenges in DMD™ Assembly and Test

, 2000
The Digital Micromirror Device™ (DMD™) developed at Texas Instruments is a spatial light modulator composed of 500,000 to 1.3 million movable micromachined aluminum mirrors.
Vincent C. Lopes, Joshua J. Malone, Armando Gonzalez, Seth A. Miller, S. Joshua Jacobs, Roger Robbins   +5 more
core   +1 more source

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia, Akash Bera, Omar Mamad, James D. Mills, Benjamin Villasana‐Salazar, Giada Lavigna, Edoardo Micotti, Manuela Conticello, Asmin Alam, Roberto Chiesa, Francesca Pagani, Roberta Frapolli, Angelo M. Lavecchia, Christodoulos Xinaris, Eleonora Aronica, Andre Altmann, Teresa Ravizza, Sanjay M. Sisodiya, David C. Henshall, Annamaria Vezzani   +19 more
wiley   +1 more source

Forage chemical composition drives early metabolic shifts in ponies fed different haylages

Equine Veterinary Journal, EarlyView.
Abstract Background Rapid changes between feeds can cause dysbiosis and colic in horses. The metabolic consequences of transitioning between haylages (HY) are currently unknown. Objectives To characterise urinary and faecal metabonomics in ponies transitioned between HY varying in botanical composition and physiological age and to evaluate the speed of
M. J. S. Moore‐Colyer, S. Daniels, P. Harris   +2 more
wiley   +1 more source

Case report: Subcutaneous emphysema following postoperative nausea

SAGE Open Medical Case Reports
Subcutaneous emphysema is a rare but potentially serious complication in dentistry and oral surgery resulting from the introduction of air into soft tissues.
Neil Ming DMD, Taha Ghouleh MD, DMD, Brian Ford MD, DMD, Steven Wang MD, DMD, Puhan He MD, DMD   +4 more
doaj   +1 more source

Structural design and 3D printing of flexible integrated electronic systems

FlexMat, EarlyView.
This review provides a comprehensive overview of design and integration strategies for individual components in flexible electronics, highlights the 3D‐printing fabrication techniques, and discusses recent advances in system‐level integration and their applications in real‐time monitoring and intelligent robotics.
Jiani Gong, Jiaying Wang, Changsong Shi, Chi Guo, Songze Fu, Jie Tao, Xiaolong Chen, Yunfei Chen, Zhiyang Lyu   +8 more
wiley   +1 more source

Real-time Reconstruction of Comminuted Mandibular Fractures Using 3D Printing

Plastic and Reconstructive Surgery, Global Open
Background:. Comminuted fractures of the jaws are complex injuries requiring special attention. In the past, treatment included closed reduction using maxillomandibular fixation. With advancements in technology and fixation systems, open reduction became
Dekel Shilo, DMD, PhD, Tal Capucha, DMD, PhD, Andrei Krasovsky, DMD, Ori Blanc, DMD, Omri Emodi, DMD, Amir Haze, MD, PhD, Adi Rachmiel, DMD, PhD   +6 more
doaj   +1 more source