Results 101 to 110 of about 51,552 (283)

ANTISENSE MEDIATED DYSTROPHIN READING FRAME RESTORATION

, 2010
Exon skipping using antisense oligonucleotides (AONs) has successfully been used to reframe the mRNA in various DMD (Duchenne muscular dystrophy) patients carrying deletions and in the mdx mouse model.
Spitali, Pietro
core  

Past and Future of Sustainability Indicator Research in Agribusiness: A Bibliometric and Forecasting Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT This study offers a forward‐looking assessment of sustainability indicator research in agribusiness by integrating bibliometric mapping with ARIMA‐based forecasting. Analysing 403 Scopus‐indexed articles, bibliographic‐coupling analysis identifies three contemporary thematic domains: Techno‐Managerial Sustainability, Systemic and ...
Marcelo Kratz Mendes, Olga Cam, Aurora Carneiro Zen, Roger de Bem Jaeger, Daniela Callegaro‐de‐Menezes, Juliana Matos de Meira   +5 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Refractive Index–Correlated Pseudocoloring for Adaptive Color Fusion in Holotomographic Cytology

Cytometry Part A, EarlyView.
ABSTRACT Conventional bright‐field (BF) cytology of thyroid fine‐needle aspiration biopsy (FNAB) suffers from staining variability and limited subcellular contrast. Here, we present a refractive index–correlated pseudocoloring (RICP) framework that integrates quantitative refractive index (RI) maps obtained by holotomography (HT) with color BF images ...
Minseok Lee, Tal Lifshitz, Young Ki Lee, Geon Kim, Seog Yun Park, Hayoung Lee, Juyeon Park, Eun Kyung Lee, YongKeun Park   +8 more
wiley   +1 more source

Revertant fibres and dystrophin traces in Duchenne muscular dystrophy: Implication for clinical trials

, 2010
Duchenne muscular dystrophy (DMD) is characterised by the absence of dystrophin in muscle biopsies, although residual dystrophin can be present, either as dystrophin-positive (revertant) fibres or traces.
Main, M, Morgan, JE, Straub, V, Feng, L, Sewry, CA, Muntoni, F, Lehovsky, J, Arechavala-Gomeza, V, Kinali, M, Hunt, D, Guglieri, M, Bushby, K, Edge, G   +12 more
core  

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

New‐Generation Integrated Devices: Multiple‐Energy Utilization and Integration Systems Based on Perovskite Photovoltaics

EcoEnergy, EarlyView.
This review highlights emerging integrated energy systems based on perovskite photovoltaics, including PSC–thermoelectric, photovoltaic–electrochemical, self‐charging, and building‐integrated architectures. By coupling multiple energy conversion and storage pathways, these multifunctional platforms enable enhanced solar utilization, improved stability,
Yihuai Huang, Wenguang Zhang, Yuchen Xiong, Zijun Yi, Changkai Huang, Qinghui Jiang, Abdul Basit, Guibin Shen, Yubo Luo, Xin Li, Junyou Yang   +10 more
wiley   +1 more source

Developing a Suitable Anion Exchange Layer Structure for Pure–Water Fed Bipolar Membrane CO2 Electrolysis

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A porous anion exchange layer (AEL) is implemented in a forward‐biased bipolar membrane CO2 electrolyzer to suppress carbonate crossover, support CO2 regeneration and maintain cathode alkalinity. Two fabrication strategies are compared—deposition on a silver gas diffusion electrode (GDE) or on the CEM—showing that a porous AEL‐coated GDE provides the ...
Henning Lorenz, Nico Roubicek, Simon Thiele, Chuyen van Pham   +3 more
wiley   +1 more source

TMJ Ankylosis as a Complication of Severe Mastoiditis in Toddlers: Pilot Study

Plastic and Reconstructive Surgery, Global Open
Background:. Acute otitis media is among the most common infections in children. Mastoiditis is a rare complication of acute otitis media in developed countries.
Omri Emodi, MD, DMD, Yair Israel, DMD, Boaz Frenkel, MD, DMD, Amir Bilder, DMD, MSc, Miri Tzemach, DMD, MSc, Tal Capucha, DMD, PhD, Andrei Krasovsky, DMD   +6 more
doaj   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo, Francesca Sardina, Maria M. Pallotta, Iñigo Marcos‐Alcalde, Paulino Gómez‐Puertas, Cinzia Rinaldo, Ian D. Krantz, Antonio Musio   +7 more
wiley   +1 more source