Results 161 to 170 of about 36,108 (238)

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

A panoramic view of the expression and function of the Doublesex/DMRT gene family in <i>C. elegans</i>. [PDF]

Sci Adv
Wang 王琛 C, Salzberg Y, Oren-Suissa M, Hobert O.   +3 more
europepmc   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

The Impact of Hydrotherapy on Health‐Related Quality of Life, Pain and Mobility in Individuals With Mucopolysaccharidosis Type II (Hunter Syndrome): A Pilot Feasibility Study

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Enzyme Replacement Therapy (ERT) is the clinical standard for Mucopolysaccharidosis II (MPSII), yet its limited penetration into poorly vascularised tissues such as bone, cartilage and heart valves leaves participants with significant musculoskeletal morbidity.
Andrew Oldham, Nicole Stockton, Mark Warburton, Calvin Heal, Marie Meehan, Karolina M. Stepien, on behalf of the MPS Society   +6 more
wiley   +1 more source

Age-related progression of myocardial dysfunction in patients with Duchenne muscular dystrophy assessed by cardiac magnetic resonance tissue tracking: a case-control study. [PDF]

Cardiovasc Diagn Ther
Liu H, Xu HY, Xu R, Fu H, Guo YK, Gong LG.   +5 more
europepmc   +1 more source

VQ‐Wave: A Physics‐Driven Spatiotemporal Deep Learning Approach for Noncontrast‐Enhanced Lung Ventilation and Perfusion MRI

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1427-1442, September 2026.
ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman, Pavlos Panos, Philipp Latzin, Oliver Bieri   +3 more
wiley   +1 more source

Transition to adulthood in Duchenne Muscular Dystrophy: a systematic review with narrative synthesis on health systems, policies, and the role of health care providers. [PDF]

Front Public Health
Friedrich S, Willems J, Rodger S, Petropoulos JA, Ringer D, Wang E, Frei J, Pozniak K, Swain A, Guastafierro E, Marcassoli A, Trucco G, Mazzilli A, Reeskau G, De Angelis F, Osman H, Fournier A, Gutierrez Rojas RG, Gorter JW, Moroni I, Leonardi M, Nardocci N, Kraus de Camargo O, Langer T.   +23 more
europepmc   +1 more source

Microbiome‐mediated chemical communication in insects: Implications for pest management

Pest Management Science, Volume 82, Issue 9, Page 8132-8151, September 2026.
Microbiome–semiochemical interactions involve the following processes: direct microbial synthesis, host gene regulation, precursor biotransformation, microbiome modulation and indirect ecological signaling. Abstract Insects rely on semiochemicals to regulate aggregation, mating, foraging, and host selection. This review synthesizes evidence that insect‐
Ioannis Eleftherianos, Wei Zhang, Amr Mohamed, Rasha K. Al‐Akeel, Abeer M. Alkhaibari, Nemat Keyhani, Guy Smagghe   +6 more
wiley   +1 more source

Elbow Flexors Muscle Fat Fraction Is a Sensitive and Relevant Outcome Measure in Nonambulant Patients With DMD. [PDF]

NMR Biomed
Michaëls M, Naarding KJ, van der Holst M, Geijsen N, Niks EH, Kan HE.   +5 more
europepmc   +1 more source