Results 191 to 200 of about 38,473 (244)

Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme)

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino, Ana Claudia P. Kravchychyn, Flávia G. Cândido, Mariana de Moura e Dias, Tiago Antônio de O. Mendes, Leandro Licursi de Oliveira, Luiza Carla V. Castro, Josefina Bressan, Ana Laura de la Garza, Fermín I. Milagro, María A. Zulet, Helen Hermana M. Hermsdorff   +11 more
wiley   +1 more source

Circulating protein biomarkers identified in two independent clinical trial cohorts of glucocorticoid-naive Duchenne muscular dystrophy patients. [PDF]

Sci Rep
Ahmadiharchegani F, Tobin RA, Degan C, Naveed A, Guglieri M, Jiménez-Requena A, de Vries SI, Szigyarto CA, Spitali P, Tsonaka R, van der Burgt YEM, Diaz-Manera J, VBP15-004 investigators, CINRG DNHS investigators, FOR-DMD investigators of the Muscle Study Group, Clemens PR, Hoffman EP, Dang UJ, Hathout Y.   +18 more
europepmc   +1 more source

SOS Dental Trauma—An Artificial Intelligence Chatbot via WhatsApp for Guiding Patients After Dental Trauma

Dental Traumatology, EarlyView.
ABSTRACT Background Traumatic dental injuries (TDIs) are highly prevalent worldwide and require immediate and appropriate management to ensure favorable outcomes. The aim of the study was to develop and validate SOS Dental Trauma, an interactive artificial intelligence‐based chatbot integrated with WhatsApp.
Luana Beatriz das Portas Luiz, Diulia Pereira Bubna, Suzanne Bettega Almeida, Flares Baratto‐Filho, Natanael Henrique Ribeiro Mattos, Manoel Damião Sousa‐Neto, Erika Calvano Küchler, Liliane Roskamp, Cristiano Miranda de Araujo, Bianca Marques de Mattos de Araujo   +9 more
wiley   +1 more source

Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior. [PDF]

Commun Biol
Karuppasamy M, English KG, Conner JR, Rorrer SN, Lopez MA, Crossman DK, Paul JR, Gutierrez-Monreal MA, Gamble KL, Esser KA, Widrick JJ, Kunkel LM, Alexander MS.   +12 more
europepmc   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

A review of recent studies on CRISPR/Cas9-mediated genome editing in a variety of muscle-related genetic disorders. [PDF]

J Transl Med
Lyu G, Li P, Lang W.
europepmc   +1 more source

Knock-Out of Specific DMD Gene Isoforms in the Parental hESC Line SA001 Using CRISPR/Cas9

Laure Chatrousse, Thifaine Poullion, Hamel Miahou, Lina El Kassar, Karine Giraud-Triboult, Claire Boissart, Alexandra Benchoua   +6 more
openalex   +1 more source

Pollution Permits and Financing Costs

Journal of Money, Credit and Banking, EarlyView.
Abstract Effective environmental policy should consider how the financiers of polluting firms behave. We study phase III of the EU Emission Trading System. Loan spreads for cap‐and‐trade participants are a function of compliance costs, permit market features, and firms’ strategic actions.
FABIO ANTONIOU, MANTHOS D. DELIS, STEVEN ONGENA, CHRIS TSOUMAS   +3 more
wiley   +1 more source

Analysis of the dystrophin, muscular dystrophy (Dmd)-dependent transcriptome in mouse gastrocnemius muscle

, 2019
JD Porter
openalex   +1 more source

A Cross‐Sectional Investigation of Rural Dental Practice as Related to Gender, Hometown, and Career Stage

Journal of Public Health Dentistry, EarlyView.
ABSTRACT Objectives This investigation explores how gender, career stage, and rurality of graduates' hometowns relate to dental practice location, specifically within Alabama's rural communities. Methods This cross‐sectional study explored demographics and practice locations for 2000–2020 graduates (N = 1233) from the state's dental school.
Carly Timmons McKenzie, Stuart Lockwood
wiley   +1 more source