Results 41 to 50 of about 130,419 (249)

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy [PDF]

, 2018
Mutations in the gene encoding dystrophin, a protein that maintains muscle integrity and function, cause Duchenne muscular dystrophy (DMD). The deltaE50-MD dog model of DMD harbors a mutation corresponding to a mutational “hotspot” in the human DMD gene.
Amoasii, L, Bassel-Duby, R, Caballero, D, Harron, R, Hildyard, J C W, Li, H, Massey, C A, Mireault, A, Olson, E N, Piercy, R J, Sanchez-Ortiz, E, Shelton, J M, Stathopoulou, T-R   +12 more
core   +2 more sources

The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations

Human Mutation, 2015
Analyzing the type and frequency of patient‐specific mutations that give rise to Duchenne muscular dystrophy (DMD) is an invaluable tool for diagnostics, basic scientific research, trial planning, and improved clinical care.
C. Bladen, D. Salgado, S. Monges, M. Foncuberta, K. Kekou, K. Kosma, H. Dawkins, Leanne Lamont, A. Roy, T. Chamova, V. Guergueltcheva, S. Chan, L. Korngut, C. Campbell, Y. Dai, Jen Wang, N. Barišić, P. Brabec, J. Lahdetie, M. Walter, O. Schreiber-Katz, V. Karcagi, M. Garami, V. Viswanathan, Farhad Bayat, F. Buccella, E. Kimura, Z. Koeks, J. C. van den Bergen, M. Rodrigues, R. Roxburgh, A. Lusakowska, A. Kostera-Pruszczyk, J. Zimowski, Rosário Santos, E. Neagu, S. Artemieva, V. Rašić, D. Vojinovic, M. Posada, C. Bloetzer, P. Jeannet, F. Joncourt, J. Díaz-Manera, E. Gallardo, A. Karaduman, H. Topaloğlu, R. El Sherif, A. Stringer, A. Shatillo, Ann S. Martin, H. Peay, M. Bellgard, J. Kirschner, K. Flanigan, V. Straub, K. Bushby, J. Verschuuren, A. Aartsma-Rus, C. Béroud, Hanns Lochmüller   +60 more
semanticscholar   +1 more source

Cloning of the DMD Gene* [PDF]

The American Journal of Human Genetics, 2005
I must start by thanking Jane Gitschier for that very kind and thorough introduction. Would you believe I have tears in my eyes? At the onset, I must say that I am extremely honored to have received the 2004 William Allan Award from the American Society of Human Genetics.
openaire   +2 more sources

Superpixel-based spatial amplitude and phase modulation using a digital micromirror device [PDF]

, 2014
We present a superpixel method for full spatial phase and amplitude control of a light beam using a digital micromirror device (DMD) combined with a spatial filter.
Bertolotti, Jacopo, Goorden, Sebastianus A., Mosk, Allard P.   +2 more
core   +3 more sources

DMD-based software-configurable spatially-offset Raman spectroscopy for spectral depth-profiling of optically turbid samples [PDF]

, 2016
Spectral depth-profiling of optically turbid samples is of high interest to a broad range of applications. We present a method for measuring spatially-offset Raman spectroscopy (SORS) over a range of length scales by incorporating a digital micro-mirror ...
Gibson, Graham, Liao, Zhiyu, Notingher, Ioan, Padgett, Miles, Sinjab, Faris   +4 more
core   +2 more sources

Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy

Disease Models & Mechanisms, 2020
Cardiomyopathy is a leading cause of early mortality in Duchenne muscular dystrophy (DMD). There is a need to gain a better understanding of the molecular pathogenesis for the development effective therapies.
Melanie Gartz, Chien-Wei Lin, M. Sussman, M. Lawlor, J. Strande   +4 more
semanticscholar   +1 more source

Path Planning of Pattern Transfer Based on Dual-Operator and a Dual-Population Ant Colony Algorithm for Digital Mask Projection Lithography

Entropy, 2020
In the process of digital micromirror device (DMD) digital mask projection lithography, the lithography efficiency will be enhanced greatly by path planning of pattern transfer.
Yingzhi Wang, Tailin Han, Xu Jiang, Yuhan Yan, Hong Liu   +4 more
doaj   +1 more source

Investigating synthetic oligonucleotide targeting of miR31 in Duchenne muscular dystrophy [PDF]

, 2016
Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne muscular dystrophy (DMD), yet this approach is highly sequence-specific and thus each oligonucleotide is of benefit to only a ...
Hildyard, J C W, Wells, D J
core   +1 more source

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method [PDF]

Molecular Therapy: Nucleic Acids, 2016
The CRISPR/Cas9 system is a great revolution in biology. This technology allows the modification of genes in vitro and in vivo in a wide variety of living organisms.
Jean-Paul Iyombe-Engembe, Dominique L. Ouellet, Xavier Barbeau, Joël Rousseau, Pierre Chapdelaine, Patrick Lagüe, Jacques P. Tremblay   +6 more
openalex   +2 more sources

Assessment of Temperature Effects in Interior Orientation Parameters Calibration of Optoelectronic Devices

Приборы и методы измерений, 2020
A digital micromirror device (DMD) micromirrors periodic spatial structure is a measuring scale in interior orientation parameters calibration of optoelectronic devices problems, when using a DMD as a testobject.
M. A. Starasotnikau
doaj   +1 more source