Results 21 to 30 of about 51,552 (283)

Experimental Studies on Suppression of Combustion Instability with the Addition of Helium [PDF]

Journal of Applied Fluid Mechanics, 2022
When combustion instability occurs, fluctuation in the release of heat couples with oscillating pressure, while the sensitivity of flame to acoustic disturbance restricts the oscillation intensity.
Y. Liu, J. Li, Z. Tian, T. Zhang, Y. Yan
doaj   +1 more source

A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy

Disease Models & Mechanisms, 2020
Duchenne muscular dystrophy (DMD) is a life-threatening neuromuscular disease caused by the lack of dystrophin, resulting in progressive muscle wasting and locomotor dysfunctions.
Tatianna Wai Ying Wong, Abdalla Ahmed, Grace Yang, Eleonora Maino, Sydney Steiman, Elzbieta Hyatt, Parry Chan, Kyle Lindsay, Nicole Wong, Diane Golebiowski, Joel Schneider, Paul Delgado-Olguín, Evgueni A. Ivakine, Ronald D. Cohn   +13 more
doaj   +1 more source

Study on characteristics of flow structure and generation of narrow-band in low-frequency noise for a slat

Xibei Gongye Daxue Xuebao, 2021
Low-frequency narrow-band noise is one of the important components in the slat noise. Based on the transient flow field analysis for multi-element airfoil 30P-30N, the main mode characteristics of the slat pressure fluctuation are analyzed by means of ...

doaj   +1 more source

DMD - BIOMARKERS [PDF]

Neuromuscular Disorders, 2021
A. Alonso-Jiménez, E. Fernández-Simón, D. Natera-De Benito, C. Ortez, C. Jimenez-Mallebrera, A. Nascimento, C. García, E. Montiel, I. Belmonte, I. Pedrosa, P. Piñol-Jurado, A. Carrasco-Rozas, X. Suárez-Calvet, C. Nuñez-Peralta, J. Llauger, P. Montesinos, J. Alonso-Pérez, E. Gallardo, I. Illa, J. Díaz-Manera   +19 more
  +10 more sources

Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress

Disease Models & Mechanisms, 2020
Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease that causes severe loss of muscle mass and function in young children. Promising therapies for DMD are being developed, but the long lead times required when using clinical outcome measures ...
Miranda D. Grounds, Jessica R. Terrill, Basma A. Al-Mshhdani, Marisa N. Duong, Hannah G. Radley-Crabb, Peter G. Arthur   +5 more
doaj   +1 more source

In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy

Molecular Therapy: Methods & Clinical Development, 2020
Delivery of therapeutic transgenes with adeno-associated viral (AAV) vectors for treatment of myopathies has yielded encouraging results in animal models and early clinical studies.
Jennifer B. Kwon, Adarsh R. Ettyreddy, Ashish Vankara, Joel D. Bohning, Garth Devlin, Stephen D. Hauschka, Aravind Asokan, Charles A. Gersbach   +7 more
doaj   +1 more source

DMD antisense oligonucleotide mediated exon skipping efficiency correlates with flanking intron retention time and target position within the exon

RNA Biology, 2023
Mutations in the DMD gene are causative for Duchenne muscular dystrophy (DMD). Antisense oligonucleotide (AON) mediated exon skipping to restore disrupted dystrophin reading frame is a therapeutic approach that allows production of a shorter but ...
Remko Goossens, Nisha Verwey, Yavuz Ariyurek, Fred Schnell, Annemieke Aartsma-Rus   +4 more
doaj   +1 more source

Application of digital micromirror devices (DMD) in biomedical instruments

Journal of Innovative Optical Health Sciences, 2020
There is an ongoing technological revolution in the field of biomedical instruments. Consequently, high performance healthcare devices have led to remarkable economic developments in the medical hardware industry.
Ziyun Zhuang, Ho Pui Ho
doaj   +1 more source

A novel custom high density-comparative genomic hybridization array detects common rearrangements as well as deep intronic mutations in dystrophinopathies [PDF]

, 2008
Background: The commonest pathogenic DMD changes are intragenic deletions/duplications which make up to 78% of all cases and point mutations (roughly 20%) detectable through direct sequencing.
McCauley, J, A. Ferlini, Martoni Elena, Cecilia Trabanelli, Ashton Emma, Ciccone, R, S. Abbs, Elena Bassi, Venturoli A, F. Muntoni, Emma Ashton, Rimessi P, Brioschi S, Neri M, Venturoli, A, Elena Martoni, Bovolenta, M, McCauley J, M. Neri, Trabanelli Cecilia, Maria S Falzarano, McCauley Joanne, Ferlini Alessandra, Muntoni Francesco, J. McCauley, Fabris M, CICCONE, ROBERTO, Merlini Luciano, Gualandi, F, Shu Yau, Yau S, Martoni, E, Paola Rimessi, Yau Shu, M. S. Falzarano, E. Martoni, Venturoli Anna, Ferlini, A, Luciano Merlini, Merlini L, Brioschi Simona, Spitali, P, Falzarano Maria S, Ciccone Roberto, Martoni E, Anna Venturoli, Spitali P, Abbs S, Marina Fabris, Sergio Fini, Abbs, S, Bassi E, Ferlini A., Ashton E, E. Bassi, Merlini, L, C. Trabanelli, Fini Sergio, M. Bovolenta, Roberto Ciccone, Fini, S, Yau, S, M. Fabris, Ashton, E, Alessandra Ferlini, L. Merlini, S. Fini, E. Ashton, Muntoni, F, Rimessi, P, Simona Brioschi, P. Rimessi, F. Gualandi, Francesco Muntoni, Brioschi, S, Neri, M, Matteo Bovolenta, Marcella Neri, Gualandi F, Bassi, E, Falzarano MS, Pietro Spitali, P. Spitali, S. Yau, Fabris, M, Abbs Stephen, S. Brioschi, Trabanelli C, Falzarano, MS, Fabris Marina, A. Venturoli, Spitali Pietro, Stephen Abbs, Francesca Gualandi, Bassi Elena, Muntoni F, Trabanelli, C, Bovolenta Matteo, Bovolenta M, Gualandi Francesca, Joanne McCauley, Neri Marcella, Rimessi Paola, Fini S   +103 more
core   +1 more source

Path Planning of Pattern Transfer Based on Dual-Operator and a Dual-Population Ant Colony Algorithm for Digital Mask Projection Lithography

Entropy, 2020
In the process of digital micromirror device (DMD) digital mask projection lithography, the lithography efficiency will be enhanced greatly by path planning of pattern transfer.
Yingzhi Wang, Tailin Han, Xu Jiang, Yuhan Yan, Hong Liu   +4 more
doaj   +1 more source